Experimental dermatophytosis on the outer ear of guinea pigs: A model that mimics natural infection

In the present study a new model of experimental dermatophytosis was tested. The aim was to achieve maximum similarity to a natural infection through a procedure that is easy to carry out. The experimental infection was induced by a single inoculation of 0.5 mL of a suspension with hyphal fragments...

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Autores principales: Oliveira dos Santos Fontenelle, Raquel, Maia de Morais, Selene, Salles de Brito, Erika Helena, Robson Falcão do Nascimento, Nilberto, Valença Júnior, José Telmo, Gadelha Rocha, Marcos Fábio
Formato: Artículo
Lenguaje:inglés
Publicado: 2014
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Acceso en línea:https://dialnet.unirioja.es/servlet/oaiart?codigo=4901405
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Sumario:In the present study a new model of experimental dermatophytosis was tested. The aim was to achieve maximum similarity to a natural infection through a procedure that is easy to carry out. The experimental infection was induced by a single inoculation of 0.5 mL of a suspension with hyphal fragments of T. mentagrophytes var. mentagrophytes on the outer ear of guinea pigs. The first signs of infection were observe on the seventh day after inoculation. The experiment demonstrated that this method, besides being effective, causes less stress and the clinical aspects the lesions here were similar to natural lesions.