Condensados Biomoleculares: Organizadores de la Vida
Life never fails to surprise us. Today, it does so with membrane-less organelles known as biomolecular condensates. These structures arise from a phenomenon of biomolecular self-organization capable of generating localized microenvironments with defined functions within the cell. In recent years,...
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| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | español |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://dialnet.unirioja.es/servlet/oaiart?codigo=9715017 |
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| Sumario: | Life never fails to surprise us. Today, it does so with membrane-less organelles known as
biomolecular condensates. These structures arise from a phenomenon of biomolecular self-organization
capable of generating localized microenvironments with defined functions within the cell. In recent years, the
significance of condensates in various aspects of cellular biology has been unveiled, including the regulation
of gene expression, protein synthesis, cellular signaling control, cytoskeletal protein polymerization, and the
formation of aggregates associated with neurodegenerative diseases, among many others yet to be discovered.
These findings are revolutionizing our current understanding of cellular processes and providing new insights
into cell process regulation. Condensates unveil previously unknown cellular mechanisms, more stochastic,
that are shifting away from the dominance of genetic mechanisms in favor of cellular self-organization
processes. The advancement in comprehending biomolecular condensates paves the way for exciting avenues
of research in cellular and molecular biology, enabling the reinterpretation of processes that relate the
genotype to the phenotype. Offering, in this way, the potential to better understand diseases and develop
more effective therapeutic approaches in the future. |
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