Impaired Physiological Regulation of ß Cells: Recent Findings from Type 2 Diabetic Patients
<p id="p1">Recent studies have emphasized the multiple aspects of non-coding micro-RNAs in the regulation of pancreatic ß cells in type 2 diabetic patients. Thus, highlighting the significance of non-coding regions of the genome in regulating pancreatic endocrine cells. Functional dysregulatio...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2024
|
| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/1136670 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | <p id="p1">Recent studies have emphasized the multiple aspects of non-coding micro-RNAs in the regulation of pancreatic ß cells in type 2 diabetic patients. Thus, highlighting the significance of non-coding regions of the genome in regulating pancreatic endocrine cells. Functional dysregulation of pancreatic endocrine cells increases the incidence of metabolic disorders in otherwise healthy individuals. A precise understanding of the molecular biology of metabolic dysregulation is important from cellular and clinical perspectives. The current chapter will highlight the important recent findings from type 2 diabetic human patients and aims to enhance our current understanding of ß cell pathophysiology from a clinical perspective for the development of novel therapeutic approaches to control this global incidence.</p> |
|---|---|
| ISBN: | 978-1-83769-628-4 |
| DOI: | 10.5772/intechopen.1003752 |