The Xiangya Lesion: A Paradigm Shift in Understanding Fungal Pathogenesis
<p id="p1">This chapter presents a comprehensive examination of the Xiangya Lesion, a novel entity resulting from the interaction between the fungus Aspergillus sydowii and human keratinocytes within plantar hyperkeratosis-like lesions. The discovery of these “zombie cells,” formed by in...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2024
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/1190102 |
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| Sumario: | <p id="p1">This chapter presents a comprehensive examination of the Xiangya Lesion, a novel entity resulting from the interaction between the fungus Aspergillus sydowii and human keratinocytes within plantar hyperkeratosis-like lesions. The discovery of these “zombie cells,” formed by integrating the fungus with the host’s cellular machinery, profoundly impacts our understanding of fungal pathogenesis, treatment modalities, and the broader evolutionary strategies of fungi within the human host. The pathogen’s intracellular nature may render traditional antifungal agents ineffective, necessitating the development of novel diagnostic techniques and therapeutic strategies to manage this condition effectively. Through an interdisciplinary exploration of the Xiangya Lesion, this chapter aims to shed light on the complex world of fungal infections and contribute to the ongoing battle between pathogen and host.</p> |
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| ISBN: | 978-0-85466-434-4 |
| DOI: | 10.5772/intechopen.1005909 |