Enhancing the Efficacy of Chemotherapeutic Drugs Via Encapsulation within Nanocomplexes Designed to Cross the Blood-Brain Barrier and Target Tumors

<p id="p1">The blood-brain barrier (BBB) blocks ~98% of drugs, so brain tumors tend to be refractory to chemotherapy. Transferrin receptors (TfRs) are expressed on the endothelial cell that comprise the BBB and mediate the movement of transferrin into the brain <em><italic xmlns:mml="http://www.w3.o...

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Autores principales: Harford, Joe B., Kim, Sang-Soo, Pirollo, Kathleen F., Rait, Antonina S., Chang, Esther H.
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2024
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Acceso en línea:https://www.intechopen.com/chapters/1201034
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