Etiological Evaluation and Management of Neonatal Seizures

<p id="p1">Neonatal seizures can be a clinical sign of a central nervous system disorder. Incidences of seizures range from 1.5 to 5.5 per 1000 in newborns. Seizures can be seen all periods of neonates, but most often occur within the first week of life. The most common cause of seizure is neonatal...

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Bibliographic Details
Main Author: Acar, Duygu
Format: Book Chapter
Language:English
Published: IntechOpen 2025
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Online Access:https://www.intechopen.com/chapters/1209751
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Summary:<p id="p1">Neonatal seizures can be a clinical sign of a central nervous system disorder. Incidences of seizures range from 1.5 to 5.5 per 1000 in newborns. Seizures can be seen all periods of neonates, but most often occur within the first week of life. The most common cause of seizure is neonatal encephalopathy and hypoxic ischemic encephalopathy. There are two types of seizures: electro-clinical and electrographic-only. Clinical types of neonatal seizures are focal clonic, focal tonic, myoclonic, epileptic spasms, and sequential seizures. Subclinical or silent seizures are now termed electrographic-only seizures. It can be hard to distinguish non-seizure paroxysmal events from seizures in the neonatal period. Multi-channel video continuous EEG (cEEG) monitoring is the gold standard for neonatal seizure diagnosis. In the management of neonatal seizures, the initial steps involve controlling the newborn&rsquo;s airway, breathing, and circulation. Phenobarbital is still the first choice of initial antiseizure medication therapy drug for infants.</p>
ISBN:978-1-83634-635-7
DOI:10.5772/intechopen.1009600