Fibroblast-Mediated Meridian and Acupoint Construction: A Review of Progress
<p>In recent years, significant progress has been made in understanding the biological basis of meridian acupoints. As a key component of connective tissue, fibroblasts play a crucial role in maintaining extracellular matrix (ECM) integrity and mediating mechanotransduction. This review explores the...
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| Autores principales: | , , , , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2025
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/1234938 |
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| Sumario: | <p>In recent years, significant progress has been made in understanding the biological basis of meridian acupoints. As a key component of connective tissue, fibroblasts play a crucial role in maintaining extracellular matrix (ECM) integrity and mediating mechanotransduction. This review explores the mechanisms by which fibroblasts contribute to the formation and function of meridian acupoints, with a particular focus on the relationship between the ECM and meridians, the role of collagen fibers in meridian signal sensing, the material basis of fascial trigger points, and the pivotal role of fibroblasts in initiating acupuncture effects. By synthesizing relevant literature, we summarize current research hotspots and emerging trends, identify key challenges and unresolved questions, and propose future research directions. As a central element in meridian acupoint function, fibroblasts may offer critical insights into the therapeutic mechanisms of acupuncture and contribute to the modern scientific interpretation of meridian theory, providing a novel perspective for interdisciplinary research.</p> |
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| ISBN: | 978-1-80631-055-5 |
| DOI: | 10.5772/intechopen.1012071 |