Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update
<p>Bone tumors (BTs) range from benign to malignant and differ in pathogenesis according to the origin of the skeletal tissue, that is, osteogenic, chondrogenic, fibrogenic, vascular, osteoclastic giant cell-rich, hematopoietic neoplasm, notochordal, and other mesenchymal tumors of bone. The locatio...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2026
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| Acceso en línea: | https://www.intechopen.com/chapters/1237112 |
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| _version_ | 1879164877112606720 |
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| author | Hafeez, Mahnoor Shahid, Ruqaiya Tanweer, Malik Osama |
| author_browse | Hafeez, Mahnoor Shahid, Ruqaiya Tanweer, Malik Osama |
| author_facet | Hafeez, Mahnoor Shahid, Ruqaiya Tanweer, Malik Osama |
| author_sort | Hafeez, Mahnoor |
| building | IntechOpen |
| collection | Acceso abierto |
| description | <p>Bone tumors (BTs) range from benign to malignant and differ in pathogenesis according to the origin of the skeletal tissue, that is, osteogenic, chondrogenic, fibrogenic, vascular, osteoclastic giant cell-rich, hematopoietic neoplasm, notochordal, and other mesenchymal tumors of bone. The location, site, and type of BT vary according to the age of the patient. The confirmatory diagnosis for malignant ones involves the combined radiological and histopathological approach, that is, radiograph, MRI, bone scan, tissue biopsy with gross specimen, microscopy, molecular biology, and immunohistochemistry (IHC). MRI is useful to assess the local extent and staging, recurrent/residual disease, and post-operative complications. CT is indicated to evaluate only few BT because of the ionizing radiation. Contrast CT chest and bone scans are indicated for metastatic work-up. Management ranges from a conservative approach, wide local excision, en bloc resection, limb salvage surgery/amputation to chemotherapy depending upon molecular markers and radiotherapy. In this chapter, authors shed the spotlight on BT, based on multi-modality and multidisciplinary collaborative pragmatic approach, with updates from current literature.</p> |
| doi_str_mv | 10.5772/intechopen.1013838 |
| first_indexed | 2026-10-15T21:41:18Z |
| format | Book Chapter |
| fullrecord | <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-1237112</identifier><datestamp>2026-04-16</datestamp>
<dc:title>Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update</dc:title>
<dc:creator>Mahnoor Hafeez</dc:creator>
<dc:creator>Ruqaiya Shahid</dc:creator>
<dc:creator>Malik Osama Tanweer</dc:creator>
<dc:subject>Health Sciences</dc:subject>
<dc:description><p>Bone tumors (BTs) range from benign to malignant and differ in pathogenesis according to the origin of the skeletal tissue, that is, osteogenic, chondrogenic, fibrogenic, vascular, osteoclastic giant cell-rich, hematopoietic neoplasm, notochordal, and other mesenchymal tumors of bone. The location, site, and type of BT vary according to the age of the patient. The confirmatory diagnosis for malignant ones involves the combined radiological and histopathological approach, that is, radiograph, MRI, bone scan, tissue biopsy with gross specimen, microscopy, molecular biology, and immunohistochemistry (IHC). MRI is useful to assess the local extent and staging, recurrent/residual disease, and post-operative complications. CT is indicated to evaluate only few BT because of the ionizing radiation. Contrast CT chest and bone scans are indicated for metastatic work-up. Management ranges from a conservative approach, wide local excision, en bloc resection, limb salvage surgery/amputation to chemotherapy depending upon molecular markers and radiotherapy. In this chapter, authors shed the spotlight on BT, based on multi-modality and multidisciplinary collaborative pragmatic approach, with updates from current literature.</p></dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2026-04-16</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/1237112</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.1013838</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-83635-977-7</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/1004493 ; Bone Tumors - Pathogenesis, Diagnosis, and Management</dc:source>
</oai_dc:dc> |
| id | intech-1237112 |
| institution | IntechOpen |
| isbn | 978-1-83635-977-7 |
| language | English |
| last_indexed | 2026-10-15T21:41:18Z |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-12371122026-04-16 Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update Mahnoor Hafeez Ruqaiya Shahid Malik Osama Tanweer Health Sciences <p>Bone tumors (BTs) range from benign to malignant and differ in pathogenesis according to the origin of the skeletal tissue, that is, osteogenic, chondrogenic, fibrogenic, vascular, osteoclastic giant cell-rich, hematopoietic neoplasm, notochordal, and other mesenchymal tumors of bone. The location, site, and type of BT vary according to the age of the patient. The confirmatory diagnosis for malignant ones involves the combined radiological and histopathological approach, that is, radiograph, MRI, bone scan, tissue biopsy with gross specimen, microscopy, molecular biology, and immunohistochemistry (IHC). MRI is useful to assess the local extent and staging, recurrent/residual disease, and post-operative complications. CT is indicated to evaluate only few BT because of the ionizing radiation. Contrast CT chest and bone scans are indicated for metastatic work-up. Management ranges from a conservative approach, wide local excision, en bloc resection, limb salvage surgery/amputation to chemotherapy depending upon molecular markers and radiotherapy. In this chapter, authors shed the spotlight on BT, based on multi-modality and multidisciplinary collaborative pragmatic approach, with updates from current literature.</p> IntechOpen 2026-04-16 Chapter, Part Of Book https://www.intechopen.com/chapters/1237112 doi:10.5772/intechopen.1013838 en ISBN:978-1-83635-977-7 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/1004493 ; Bone Tumors - Pathogenesis, Diagnosis, and Management |
| spellingShingle | Health Sciences Hafeez, Mahnoor Shahid, Ruqaiya Tanweer, Malik Osama Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title | Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title_full | Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title_fullStr | Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title_full_unstemmed | Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title_short | Clinical and Radio-pathological Spectrum of Bone Tumors: Review and Update |
| title_sort | clinical and radio pathological spectrum of bone tumors review and update |
| topic | Health Sciences |
| url | https://www.intechopen.com/chapters/1237112 |
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