Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences
<p>Neurosurgical therapy of movement disorders experienced a renaissance with the introduction of deep brain stimulation (DBS) in the 1980s. DBS aimed to improve symptoms in Parkinson’s disease, tremor, and dystonia, which are among the most important indications. With advances in brain MRI an...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2026
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| Acceso en línea: | https://www.intechopen.com/chapters/1246521 |
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| _version_ | 1879164894758043648 |
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| author | Drucks, Bea Mehdorn, Hubertus Maximilian Luebbing, Isabel |
| author_browse | Drucks, Bea Luebbing, Isabel Mehdorn, Hubertus Maximilian |
| author_facet | Drucks, Bea Mehdorn, Hubertus Maximilian Luebbing, Isabel |
| author_sort | Drucks, Bea |
| building | IntechOpen |
| collection | Acceso abierto |
| description | <p>Neurosurgical therapy of movement disorders experienced a renaissance with the introduction of deep brain stimulation (DBS) in the 1980s. DBS aimed to improve symptoms in Parkinson’s disease, tremor, and dystonia, which are among the most important indications. With advances in brain MRI and the implementation of real-time intracerebral temperature monitoring, focused ultrasound has again expanded treatment options by broadening the neurosurgical therapeutic armamentarium. Having started DBS in 1999 and having contributed extensively to the scientific literature together with our neurological colleagues, we have, since 2020, also used MR-guided focused ultrasound (MRgFUS) to treat patients with tremor by targeting the ventral intermediate nucleus (VIM; nucleus ventralis intermedius) and patients with Parkinson’s disease by targeting the subthalamic nucleus (STN; nucleus subthalamicus). Differential indications for DBS and MRgFUS will be reviewed, and experiences from a high-volume center with more than 1,500 patients treated by either method will be described.</p> |
| doi_str_mv | 10.5772/intechopen.1015010 |
| first_indexed | 2026-10-15T21:41:35Z |
| format | Book Chapter |
| fullrecord | <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-1246521</identifier><datestamp>2026-04-09</datestamp>
<dc:title>Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences</dc:title>
<dc:creator>Bea Drucks</dc:creator>
<dc:creator>Hubertus Maximilian Mehdorn</dc:creator>
<dc:creator>Isabel Luebbing</dc:creator>
<dc:subject>Health Sciences</dc:subject>
<dc:description><p>Neurosurgical therapy of movement disorders experienced a renaissance with the introduction of deep brain stimulation (DBS) in the 1980s. DBS aimed to improve symptoms in Parkinson&rsquo;s disease, tremor, and dystonia, which are among the most important indications. With advances in brain MRI and the implementation of real-time intracerebral temperature monitoring, focused ultrasound has again expanded treatment options by broadening the neurosurgical therapeutic armamentarium. Having started DBS in 1999 and having contributed extensively to the scientific literature together with our neurological colleagues, we have, since 2020, also used MR-guided focused ultrasound (MRgFUS) to treat patients with tremor by targeting the ventral intermediate nucleus (VIM; nucleus ventralis intermedius) and patients with Parkinson&rsquo;s disease by targeting the subthalamic nucleus (STN; nucleus subthalamicus). Differential indications for DBS and MRgFUS will be reviewed, and experiences from a high-volume center with more than 1,500 patients treated by either method will be described.</p></dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2026-04-09</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/1246521</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.1015010</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80631-853-7</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/1005063 ; Neurosurgical Procedures - Understanding and Advancements</dc:source>
</oai_dc:dc> |
| id | intech-1246521 |
| institution | IntechOpen |
| isbn | 978-1-80631-853-7 |
| language | English |
| last_indexed | 2026-10-15T21:41:35Z |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-12465212026-04-09 Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences Bea Drucks Hubertus Maximilian Mehdorn Isabel Luebbing Health Sciences <p>Neurosurgical therapy of movement disorders experienced a renaissance with the introduction of deep brain stimulation (DBS) in the 1980s. DBS aimed to improve symptoms in Parkinson’s disease, tremor, and dystonia, which are among the most important indications. With advances in brain MRI and the implementation of real-time intracerebral temperature monitoring, focused ultrasound has again expanded treatment options by broadening the neurosurgical therapeutic armamentarium. Having started DBS in 1999 and having contributed extensively to the scientific literature together with our neurological colleagues, we have, since 2020, also used MR-guided focused ultrasound (MRgFUS) to treat patients with tremor by targeting the ventral intermediate nucleus (VIM; nucleus ventralis intermedius) and patients with Parkinson’s disease by targeting the subthalamic nucleus (STN; nucleus subthalamicus). Differential indications for DBS and MRgFUS will be reviewed, and experiences from a high-volume center with more than 1,500 patients treated by either method will be described.</p> IntechOpen 2026-04-09 Chapter, Part Of Book https://www.intechopen.com/chapters/1246521 doi:10.5772/intechopen.1015010 en ISBN:978-1-80631-853-7 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/1005063 ; Neurosurgical Procedures - Understanding and Advancements |
| spellingShingle | Health Sciences Drucks, Bea Mehdorn, Hubertus Maximilian Luebbing, Isabel Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title | Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title_full | Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title_fullStr | Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title_full_unstemmed | Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title_short | Deep brain stimulation and MRI-guided focused ultrasound for movement disorders – neurosurgical considerations and institutional experiences |
| title_sort | deep brain stimulation and mri guided focused ultrasound for movement disorders neurosurgical considerations and institutional experiences |
| topic | Health Sciences |
| url | https://www.intechopen.com/chapters/1246521 |
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