T Cell Exhaustion in Chronic Infectious Diseases: Mechanisms, Tissue-Specific Programming and Therapeutic Opportunities

<p>T cell exhaustion has emerged as a distinct differentiation program that arises in settings of sustained antigenic stimulation, chronic tissue remodeling, and complex regulatory tissue microenvironments. In chronic infectious diseases, including persistent viral infections, tuberculosis, visceral...

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Bibliographic Details
Main Author: Carregaro, Vanessa
Format: Book Chapter
Language:English
Published: IntechOpen 2026
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Online Access:https://www.intechopen.com/chapters/1247147
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