Laboratory analysis of mycotoxins: Foundations, methods and advances
<p>Mycotoxin contamination in food commodities poses threats to global food safety, public health, and economic stability. This review describes the usual workflow of mycotoxin laboratory analysis including sampling, homogenization, extraction, cleanup, chromatographic separation, and final detectio...
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| Autores principales: | , , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2026
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/1248701 |
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| Sumario: | <p>Mycotoxin contamination in food commodities poses threats to global food safety, public health, and economic stability. This review describes the usual workflow of mycotoxin laboratory analysis including sampling, homogenization, extraction, cleanup, chromatographic separation, and final detection. It presents common analytical techniques, such as high-performance liquid chromatography (HPLC), thin-layer chromatography (TLC), gas chromatography (GC), and tandem mass spectrometry (LC-MS/MS) highlighted as the gold standard for multi-mycotoxin identification and confirmatory testing due to its superior sensitivity and specificity. Rapid on-site detection tools, such as enzyme-linked immunosorbent assay (ELISA), lateral flow assays (LFAs), and nanomaterial-enhanced biosensors, are also emphasized for their practical utility in rapid screening. Meanwhile, it faces critical analytical challenges including the co-occurrence of multiple mycotoxins, the undetectability of modified/masked mycotoxin derivatives, and the scarcity of certified reference standards. Emerging technological advancements, AI-driven spectroscopic detection, nanomaterial-based sensing, and automated analytical workflows, are discussed as promising solutions to these challenges. Additionally, the indispensability of robust quality control, method validation, and compliance with global regulatory standards are required to ensure the reliability and comparability of test results. Future perspectives for mycotoxin analysis may focus on the development of targeted detection for emerging toxins, commercialization of rapid on-site technologies, and integration of artificial intelligence for predictive contamination risk assessment.</p> |
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| ISBN: | 978-1-80631-643-4 |
| DOI: | 10.5772/intechopen.1015072 |