NQO1-Bioactivatable Therapeutics as Radiosensitizers for Cancer Treatment

Developing cancer therapeutics that radiosensitize in a tumor-selective manner remains an ideal. We developed a novel means of radiosensitization, exploiting NAD(P)H:Quinone Oxidoreductase 1 (NQO1) overexpression, and lowered catalase expression in solid human tumors using NQO1-bioactivatable drugs....

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Detalles Bibliográficos

Autores principales:	Singh, Naveen, Motea, Edward A., Huang, Xiumei, Starcher, Colton L., Silver, Jayne, Yeh, I-Ju, Pay, S. Louise, Su, Xiaolin, Russ, Kristen A., Boothman, David A., Bey, Erik A.
Formato:	Capítulo de libro
Lenguaje:	inglés
Publicado:	IntechOpen 2020
Materias:	Life Sciences
Acceso en línea:	https://www.intechopen.com/chapters/70814
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