Immunogenetic Aspect of B-Cell Antigen Receptor Diversity Generation
The generation of antigen receptor diversity, and thus of the B-cell repertoire, is the result of very complex immunogenetic mechanisms. So, this chapter gives a brief overview on immunoglobulin (IG) gene organization and gene rearrangements, as well as the main mechanisms of immunoglobulin repertoi...
Saved in:
| Main Author: | |
|---|---|
| Format: | Book Chapter |
| Language: | English |
| Published: |
IntechOpen
2020
|
| Subjects: | |
| Online Access: | https://www.intechopen.com/chapters/70842 |
| Tags: |
No Tags, Be the first to tag this record!
|
| Summary: | The generation of antigen receptor diversity, and thus of the B-cell repertoire, is the result of very complex immunogenetic mechanisms. So, this chapter gives a brief overview on immunoglobulin (IG) gene organization and gene rearrangements, as well as the main mechanisms of immunoglobulin repertoire development. |
|---|---|
| ISBN: | 978-1-78985-430-5 |
| DOI: | 10.5772/intechopen.90637 |