Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD

Our chapter contends that extended intranasal insulin administration can preserve pragmatic functioning even when there are temporal lobe and frontal lobe brain volume losses consistent with AD disease progression. CT scans of a patient receiving extended intranasal insulin 6 years after AD diagnosi...

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Main Author: Schatz, Sara
Format: Book Chapter
Language:English
Published: IntechOpen 2020
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Online Access:https://www.intechopen.com/chapters/71049
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author Schatz, Sara
author_browse Schatz, Sara
author_facet Schatz, Sara
author_sort Schatz, Sara
building IntechOpen
collection Acceso abierto
description Our chapter contends that extended intranasal insulin administration can preserve pragmatic functioning even when there are temporal lobe and frontal lobe brain volume losses consistent with AD disease progression. CT scans of a patient receiving extended intranasal insulin 6 years after AD diagnosis are compared with his CT scans at the original MCI diagnosis. The results demonstrate that areas of the brain associated with pragmatic functioning were not as affected as expected in late-stage AD patients. This, along with linguistic evidence of preserved pragmatic competence, indicates the likely effectiveness of intranasal insulin treatment in enhancing neuronal activity in certain areas of the brain associated with pragmatic competence.
doi_str_mv 10.5772/intechopen.90725
first_indexed 2026-10-15T21:38:28Z
format Book Chapter
fullrecord <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-71049</identifier><datestamp>2020-02-12</datestamp> <dc:title>Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD</dc:title> <dc:creator>Sara Schatz</dc:creator> <dc:subject>Life Sciences</dc:subject> <dc:description>Our chapter contends that extended intranasal insulin administration can preserve pragmatic functioning even when there are temporal lobe and frontal lobe brain volume losses consistent with AD disease progression. CT scans of a patient receiving extended intranasal insulin 6 years after AD diagnosis are compared with his CT scans at the original MCI diagnosis. The results demonstrate that areas of the brain associated with pragmatic functioning were not as affected as expected in late-stage AD patients. This, along with linguistic evidence of preserved pragmatic competence, indicates the likely effectiveness of intranasal insulin treatment in enhancing neuronal activity in certain areas of the brain associated with pragmatic competence.</dc:description> <dc:publisher>IntechOpen</dc:publisher> <dc:date>2020-02-12</dc:date> <dc:type>Chapter, Part Of Book</dc:type> <dc:identifier>https://www.intechopen.com/chapters/71049</dc:identifier> <dc:identifier>doi:10.5772/intechopen.90725</dc:identifier> <dc:language>en</dc:language> <dc:relation>ISBN:978-1-83880-291-2</dc:relation> <dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights> <dc:source>https://www.intechopen.com/books/8059 ; Neurostimulation and Neuromodulation in Contemporary Therapeutic Practice</dc:source> </oai_dc:dc>
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spelling intech-710492020-02-12 Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD Sara Schatz Life Sciences Our chapter contends that extended intranasal insulin administration can preserve pragmatic functioning even when there are temporal lobe and frontal lobe brain volume losses consistent with AD disease progression. CT scans of a patient receiving extended intranasal insulin 6 years after AD diagnosis are compared with his CT scans at the original MCI diagnosis. The results demonstrate that areas of the brain associated with pragmatic functioning were not as affected as expected in late-stage AD patients. This, along with linguistic evidence of preserved pragmatic competence, indicates the likely effectiveness of intranasal insulin treatment in enhancing neuronal activity in certain areas of the brain associated with pragmatic competence. IntechOpen 2020-02-12 Chapter, Part Of Book https://www.intechopen.com/chapters/71049 doi:10.5772/intechopen.90725 en ISBN:978-1-83880-291-2 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/8059 ; Neurostimulation and Neuromodulation in Contemporary Therapeutic Practice
spellingShingle Life Sciences
Schatz, Sara
Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title_full Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title_fullStr Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title_full_unstemmed Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title_short Intranasal Insulin as Promising Therapy for Preserving Pragmatic Competence in MCI and AD
title_sort intranasal insulin as promising therapy for preserving pragmatic competence in mci and ad
topic Life Sciences
url https://www.intechopen.com/chapters/71049
work_keys_str_mv AT schatzsara intranasalinsulinaspromisingtherapyforpreservingpragmaticcompetenceinmciandad