Metformin Activity against Breast Cancer: Mechanistic Differences by Molecular Subtype and Metabolic Conditions

Obesity and type 2 diabetes increase the risk of and reduce survival in breast cancer (BC) patients. Metformin is the only anti-diabetic drug that alters this risk, with a reduction in BC incidence and improved outcomes. Metformin has AMP-kinase (AMPK) dependent and independent mechanisms of action,...

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Autores principales: Wahdan-Alaswad, Reema S., Thor, Ann D.
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/71075
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