Cell-Penetrating Peptides: A Challenge for Drug Delivery
Cell-penetrating peptide (CPP) is a term that describes relatively short amphipathic and cationic peptides (7–30 amino acid residues) with rapid translocation across the cell membrane. They can be used to deliver molecular bioactive cargoes due to their efficacy in cellular internalization and also...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2020
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/71466 |
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| Sumario: | Cell-penetrating peptide (CPP) is a term that describes relatively short amphipathic and cationic peptides (7–30 amino acid residues) with rapid translocation across the cell membrane. They can be used to deliver molecular bioactive cargoes due to their efficacy in cellular internalization and also to their low cytotoxicity. In this review we provide an overview of the current approaches and describe the potential of CPP-based drug delivery systems and indicate their powerful promise for clinical efficacy. |
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| ISBN: | 978-1-83880-067-3 |
| DOI: | 10.5772/intechopen.91684 |