Allosteric Modulators for GPCRs as a Therapeutic Alternative with High Potential in Drug Discovery

The superfamily of G protein-coupled receptors (GPCRs) consists of biological microprocessors that can activate multiple signaling pathways. Most GPCRs have an orthosteric pocket where the endogenous ligand(s) typically binds. Conversely, allosteric ligands bind to GPCRs at sites that are distinct f...

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Autores principales:	Reyes-Alcaraz, Arfaxad, Garcia-Rojas, Emilio Y. Lucero, Bond, Richard A., McConnell, Bradley K.
Formato:	Capítulo de libro
Lenguaje:	inglés
Publicado:	IntechOpen 2020
Materias:	Health Sciences
Acceso en línea:	https://www.intechopen.com/chapters/71546
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