Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia

The spectacular progress which was present in the past few years in the field of genome sequencing, together with the appearance on the market of some high performance devices in this field, the reduction of the costs regarding the analysis of the samples and the standardization of some protocols, h...

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Autores principales: Boldura, Oana Maria, Petrine, Cristina, Mihu, Alin, Balta, Cornel
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Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/71721
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author Boldura, Oana Maria
Petrine, Cristina
Mihu, Alin
Balta, Cornel
author_browse Balta, Cornel
Boldura, Oana Maria
Mihu, Alin
Petrine, Cristina
author_facet Boldura, Oana Maria
Petrine, Cristina
Mihu, Alin
Balta, Cornel
author_sort Boldura, Oana Maria
building IntechOpen
collection Acceso abierto
description The spectacular progress which was present in the past few years in the field of genome sequencing, together with the appearance on the market of some high performance devices in this field, the reduction of the costs regarding the analysis of the samples and the standardization of some protocols, has led to the establishment and introduction of the new generation of sequencing techniques in clinical diagnostic labs. An important role is played by the implementation of this technique in the oncology clinics. In this context, we found it appropriate to discuss in this chapter about the role of next-gen sequencing in determining the genetic probabilities of occurrence of oncological pathologies in the healthy population, the screening of these diseases at the population level, the diagnosis and classification of this pathology, the establishment of the therapeutic conduct using the technique, as well as the progression of the disease. In this chapter, we intend to discuss in particular the involvement of this technology in hemato-oncological diseases.
doi_str_mv 10.5772/intechopen.92068
first_indexed 2026-10-15T21:38:35Z
format Book Chapter
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spelling intech-717212020-04-08 Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia Oana Maria Boldura Cristina Petrine Alin Mihu Cornel Balta Life Sciences The spectacular progress which was present in the past few years in the field of genome sequencing, together with the appearance on the market of some high performance devices in this field, the reduction of the costs regarding the analysis of the samples and the standardization of some protocols, has led to the establishment and introduction of the new generation of sequencing techniques in clinical diagnostic labs. An important role is played by the implementation of this technique in the oncology clinics. In this context, we found it appropriate to discuss in this chapter about the role of next-gen sequencing in determining the genetic probabilities of occurrence of oncological pathologies in the healthy population, the screening of these diseases at the population level, the diagnosis and classification of this pathology, the establishment of the therapeutic conduct using the technique, as well as the progression of the disease. In this chapter, we intend to discuss in particular the involvement of this technology in hemato-oncological diseases. IntechOpen 2020-04-08 Chapter, Part Of Book https://www.intechopen.com/chapters/71721 doi:10.5772/intechopen.92068 en ISBN:978-1-78984-856-4 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/8912 ; Biochemical Analysis Tools - Methods for Bio-Molecules Studies
spellingShingle Life Sciences
Boldura, Oana Maria
Petrine, Cristina
Mihu, Alin
Balta, Cornel
Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title_full Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title_fullStr Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title_full_unstemmed Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title_short Latest Implications of Next-Gen Sequencing in Diagnosis of Acute and Chronic Myeloid Leukemia
title_sort latest implications of next gen sequencing in diagnosis of acute and chronic myeloid leukemia
topic Life Sciences
url https://www.intechopen.com/chapters/71721
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AT petrinecristina latestimplicationsofnextgensequencingindiagnosisofacuteandchronicmyeloidleukemia
AT mihualin latestimplicationsofnextgensequencingindiagnosisofacuteandchronicmyeloidleukemia
AT baltacornel latestimplicationsofnextgensequencingindiagnosisofacuteandchronicmyeloidleukemia