Integrated Molecular Profiling as an Approach to Identify PI3K Inhibitor Resistance Mechanisms

The identification of drug resistance pathways and approaches to target these pathways remains a significant and important challenge in cancer biology. Here, we address this challenge in the context of ongoing efforts to advance phosphatidylinositol 3-kinase (PI3K) inhibitors for the treatment of PI...

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Autores principales: Michmerhuizen, Nicole L., Wang, Jiayu, Brenner, J. Chad
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/72692
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