KRas4BG12C/D/PDE6δ Heterodimeric Molecular Complex: A Target Molecular Multicomplex for the Identification and Evaluation of Nontoxic Pharmacological Compounds for the Treatment of Pancreatic Cancer

The search for new targeted therapies to improve the quality of life of patients with pancreatic cancer has taken about 30 years. Compounds that can inhibit the K-Ras4B oncoprotein signaling pathway have been sought. Taking into account that the interaction of KRas4B with PDE6δ is essential for its...

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Autores principales: Briseño-Díaz, Paola, Velez-Uriza, Dora Emma, Cruz-Nova, Pedro, Ramirez, Martiniano Bello, Correa-Basurto, Jose, Hernandez-Rivas, Rosaura, Bonilla, Ma del Rocio Thompson, Mejía, Miguel Ángel Vargas
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2020
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Acceso en línea:https://www.intechopen.com/chapters/73023
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