Molecular Mechanisms of Polyglutamine Pathology and Lessons Learned from Huntington’s Disease
Identification of polymorphic repeating units on DNA as a cause of many neurological disorders has introduced a new concept in molecular biology: Dynamic mutations. Many of the identified dynamic mutations involve expansion of trinucleotide repeats within disease genes. Nine neurodegenerative disord...
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| Format: | Book Chapter |
| Language: | English |
| Published: |
IntechOpen
2020
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| Online Access: | https://www.intechopen.com/chapters/74067 |
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