Targeting MYC and HDAC8 with a Combination of siRNAs Inhibits Neuroblastoma Cells Proliferation In Vitro and In Vivo Xenograft Tumor Growth
HDAC8, c MYC and MYCN are involved in the tumorigenesis of neuroblastoma. A mouse Neuroblastoma (NB) tumor model was used to understand the role of miRNA, miR-665 in NB tumorigenesis and cellular differentiation. During cellular differentiation of NB cells there is an up regulated miRNA-665. We foun...
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2021
|
| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/75151 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares: Targeting MYC and HDAC8 with a Combination of siRNAs Inhibits Neuroblastoma Cells Proliferation In Vitro and In Vivo Xenograft Tumor Growth
- Computational Approaches for Designing Efficient and Specific siRNAs
- Lactobacillus as Epigenetic Architects: Butyrate-Driven HDAC Inhibition and Multiaxis Metabolic Reprogramming
- Xenograft Model of Human Brain Tumor
- miRNAs as Essential Mediators of the Actions of Retinoic Acid in Neuroblastoma Cells
- Chitosan-DNA/siRNA Nanoparticles for Gene Therapy
- siRNA and Gene Formulation for Efficient Gene Therapy