Recent Advances in Targeting Clinical Volatile Organic Compounds (VOC)

This chapter introduces the significance of exploring volatile organic compounds (VOC) in clinical samples. Because exhaled-breath is easy to collect, unlimited, and instruments are already commercially available, VOC analysis in exhaled breath seems to be a promising tool for non-invasive detection...

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Detalles Bibliográficos
Autores principales: Azzouz, Imadeddine, Khan, Mohammad Sharif, Bishop, Andrew C., Bachari, Khaldoun
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2021
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Acceso en línea:https://www.intechopen.com/chapters/75410
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Descripción
Sumario:This chapter introduces the significance of exploring volatile organic compounds (VOC) in clinical samples. Because exhaled-breath is easy to collect, unlimited, and instruments are already commercially available, VOC analysis in exhaled breath seems to be a promising tool for non-invasive detection of many diseases including infections, respiratory diseases, and cancers. Here, we have focused on some appropriate technologies to extract, pre-concentrate, and evaluate VOC biomarkers in exhaled breath. The second part of this chapter discusses the comprehensive GC × GC in bio-VOCs analysis and illustrates the potential of using this analytical technique.
ISBN:978-1-83962-602-9
DOI:10.5772/intechopen.96436