Evolutionary Conservation of the Role of CD4 as a Receptor for Interleukin-16

The interaction of CD4 with MHC class II during helper T-cell activation and effector function is required for the initiation of an adaptive immune response in all gnathostomes. CD4 is comprised of four immunoglobulin domains but most likely arose from an ancestral two-domain homolog. The distal, D1...

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Detalles Bibliográficos

Autor principal:	Maniero, Gregory D.
Formato:	Capítulo de libro
Lenguaje:	inglés
Publicado:	IntechOpen 2021
Materias:	Health Sciences
Acceso en línea:	https://www.intechopen.com/chapters/75756
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