Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases

The theoretical discovery of Sanal flow choking in the cardiovascular system (CVS) demands for interdisciplinary studies and universal actions to propose modern medications and to discover new drugs to annul the risk of flow-choking leading to shock-wave generation causing asymptomatic-cardiovascula...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kumar, Valsalayam Raghavapanicker Sanal, Choudhary, Shiv Kumar, Radhakrishnan, Pradeep Kumar, Bharath, Rajaghatta Sundararam, Chandrasekaran, Nichith, Sankar, Vigneshwaran, Sukumaran, Ajith, Oommen, Charlie
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2021
Materias:
Acceso en línea:https://www.intechopen.com/chapters/75813
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1879164716126830593
author Kumar, Valsalayam Raghavapanicker Sanal
Choudhary, Shiv Kumar
Radhakrishnan, Pradeep Kumar
Bharath, Rajaghatta Sundararam
Chandrasekaran, Nichith
Sankar, Vigneshwaran
Sukumaran, Ajith
Oommen, Charlie
author_browse Bharath, Rajaghatta Sundararam
Chandrasekaran, Nichith
Choudhary, Shiv Kumar
Kumar, Valsalayam Raghavapanicker Sanal
Oommen, Charlie
Radhakrishnan, Pradeep Kumar
Sankar, Vigneshwaran
Sukumaran, Ajith
author_facet Kumar, Valsalayam Raghavapanicker Sanal
Choudhary, Shiv Kumar
Radhakrishnan, Pradeep Kumar
Bharath, Rajaghatta Sundararam
Chandrasekaran, Nichith
Sankar, Vigneshwaran
Sukumaran, Ajith
Oommen, Charlie
author_sort Kumar, Valsalayam Raghavapanicker Sanal
building IntechOpen
collection Acceso abierto
description The theoretical discovery of Sanal flow choking in the cardiovascular system (CVS) demands for interdisciplinary studies and universal actions to propose modern medications and to discover new drugs to annul the risk of flow-choking leading to shock-wave generation causing asymptomatic-cardiovascular-diseases. In this chapter we show that when blood-pressure-ratio (BPR) reaches the lower-critical-hemorrhage-index (LCHI) the flow-choking could occur in the CVS with and without stent. The flow-choking is uniquely regulated by the biofluid/blood-heat-capacity-ratio (BHCR). The BHCR is well correlated with BPR, blood-viscosity and ejection-fraction. The closed-form analytical models reveal that the relatively high and the low blood-viscosity are cardiovascular-risk factors. In vitro data shows that nitrogen, oxygen, and carbon dioxide gases are predominant in fresh blood samples of the human being/Guinea-pig at a temperature range of 37–40 °C (98.6–104 °F). In silico results demonstrate the occurrence of Sanal flow choking leading to shock wave generation and pressure-overshoot in CVS without any apparent occlusion. We could conclude authoritatively, without any ex vivo or in vivo studies, that the Sanal flow choking in CVS leads to asymptomatic-cardiovascular-diseases. The cardiovascular-risk could be diminished by concurrently lessening the viscosity of biofluid/blood and flow-turbulence by increasing the thermal-tolerance level in terms of BHCR and/or by decreasing the BPR.
doi_str_mv 10.5772/intechopen.96987
first_indexed 2026-10-15T21:38:45Z
format Book Chapter
fullrecord <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-75813</identifier><datestamp>2021-03-19</datestamp> <dc:title>Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases</dc:title> <dc:creator>Valsalayam Raghavapanicker Sanal Kumar</dc:creator> <dc:creator>Shiv Kumar Choudhary</dc:creator> <dc:creator>Pradeep Kumar Radhakrishnan</dc:creator> <dc:creator>Rajaghatta Sundararam Bharath</dc:creator> <dc:creator>Nichith Chandrasekaran</dc:creator> <dc:creator>Vigneshwaran Sankar</dc:creator> <dc:creator>Ajith Sukumaran</dc:creator> <dc:creator>Charlie Oommen</dc:creator> <dc:subject>Health Sciences</dc:subject> <dc:description>The theoretical discovery of Sanal flow choking in the cardiovascular system (CVS) demands for interdisciplinary studies and universal actions to propose modern medications and to discover new drugs to annul the risk of flow-choking leading to shock-wave generation causing asymptomatic-cardiovascular-diseases. In this chapter we show that when blood-pressure-ratio (BPR) reaches the lower-critical-hemorrhage-index (LCHI) the flow-choking could occur in the CVS with and without stent. The flow-choking is uniquely regulated by the biofluid/blood-heat-capacity-ratio (BHCR). The BHCR is well correlated with BPR, blood-viscosity and ejection-fraction. The closed-form analytical models reveal that the relatively high and the low blood-viscosity are cardiovascular-risk factors. In vitro data shows that nitrogen, oxygen, and carbon dioxide gases are predominant in fresh blood samples of the human being/Guinea-pig at a temperature range of 37–40 °C (98.6–104 °F). In silico results demonstrate the occurrence of Sanal flow choking leading to shock wave generation and pressure-overshoot in CVS without any apparent occlusion. We could conclude authoritatively, without any ex vivo or in vivo studies, that the Sanal flow choking in CVS leads to asymptomatic-cardiovascular-diseases. The cardiovascular-risk could be diminished by concurrently lessening the viscosity of biofluid/blood and flow-turbulence by increasing the thermal-tolerance level in terms of BHCR and/or by decreasing the BPR.</dc:description> <dc:publisher>IntechOpen</dc:publisher> <dc:date>2021-03-19</dc:date> <dc:type>Chapter, Part Of Book</dc:type> <dc:identifier>https://www.intechopen.com/chapters/75813</dc:identifier> <dc:identifier>doi:10.5772/intechopen.96987</dc:identifier> <dc:language>en</dc:language> <dc:relation>ISBN:978-1-83968-161-5</dc:relation> <dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights> <dc:source>https://www.intechopen.com/books/9578 ; Cardiac Diseases - Novel Aspects of Cardiac Risk, Cardiorenal Pathology and Cardiac Interventions</dc:source> </oai_dc:dc>
id intech-75813
institution IntechOpen
isbn 978-1-83968-161-5
language English
last_indexed 2026-10-15T21:38:45Z
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher IntechOpen
publisherStr IntechOpen
record_format oai_dc
spelling intech-758132021-03-19 Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases Valsalayam Raghavapanicker Sanal Kumar Shiv Kumar Choudhary Pradeep Kumar Radhakrishnan Rajaghatta Sundararam Bharath Nichith Chandrasekaran Vigneshwaran Sankar Ajith Sukumaran Charlie Oommen Health Sciences The theoretical discovery of Sanal flow choking in the cardiovascular system (CVS) demands for interdisciplinary studies and universal actions to propose modern medications and to discover new drugs to annul the risk of flow-choking leading to shock-wave generation causing asymptomatic-cardiovascular-diseases. In this chapter we show that when blood-pressure-ratio (BPR) reaches the lower-critical-hemorrhage-index (LCHI) the flow-choking could occur in the CVS with and without stent. The flow-choking is uniquely regulated by the biofluid/blood-heat-capacity-ratio (BHCR). The BHCR is well correlated with BPR, blood-viscosity and ejection-fraction. The closed-form analytical models reveal that the relatively high and the low blood-viscosity are cardiovascular-risk factors. In vitro data shows that nitrogen, oxygen, and carbon dioxide gases are predominant in fresh blood samples of the human being/Guinea-pig at a temperature range of 37–40 °C (98.6–104 °F). In silico results demonstrate the occurrence of Sanal flow choking leading to shock wave generation and pressure-overshoot in CVS without any apparent occlusion. We could conclude authoritatively, without any ex vivo or in vivo studies, that the Sanal flow choking in CVS leads to asymptomatic-cardiovascular-diseases. The cardiovascular-risk could be diminished by concurrently lessening the viscosity of biofluid/blood and flow-turbulence by increasing the thermal-tolerance level in terms of BHCR and/or by decreasing the BPR. IntechOpen 2021-03-19 Chapter, Part Of Book https://www.intechopen.com/chapters/75813 doi:10.5772/intechopen.96987 en ISBN:978-1-83968-161-5 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/9578 ; Cardiac Diseases - Novel Aspects of Cardiac Risk, Cardiorenal Pathology and Cardiac Interventions
spellingShingle Health Sciences
Kumar, Valsalayam Raghavapanicker Sanal
Choudhary, Shiv Kumar
Radhakrishnan, Pradeep Kumar
Bharath, Rajaghatta Sundararam
Chandrasekaran, Nichith
Sankar, Vigneshwaran
Sukumaran, Ajith
Oommen, Charlie
Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title_full Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title_fullStr Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title_full_unstemmed Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title_short Internal Flow Choking in Cardiovascular System: A Radical Theory in the Risk Assessment of Asymptomatic Cardiovascular Diseases
title_sort internal flow choking in cardiovascular system a radical theory in the risk assessment of asymptomatic cardiovascular diseases
topic Health Sciences
url https://www.intechopen.com/chapters/75813
work_keys_str_mv AT kumarvalsalayamraghavapanickersanal internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT choudharyshivkumar internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT radhakrishnanpradeepkumar internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT bharathrajaghattasundararam internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT chandrasekarannichith internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT sankarvigneshwaran internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT sukumaranajith internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases
AT oommencharlie internalflowchokingincardiovascularsystemaradicaltheoryintheriskassessmentofasymptomaticcardiovasculardiseases