Role of RUNX2 in Melanoma: A New Player in Tumor Progression and Resistance to Therapy

RUNX2, a transcription factor, initially known for its indispensable role in skeletal development. RUNX2 is essential for osteoblast differentiation and the maintain of the osteocyte balance. RUNX2 acts directly on osteoblasts via Fgf pathway or on mesenchymal progenitors through Hedgehog, Wnt, Pthl...

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Autores principales: Pulica, Rachael, Solal, Karine Cohen, Lasfar, Ahmed
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2021
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Acceso en línea:https://www.intechopen.com/chapters/76184
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