Exercise Therapy for Patients with Heart Failure: Focusing on the Pathophysiology of Skeletal Muscle

In patients with heart failure (HF), it is important to perform exercise therapy with a focus on the pathophysiology of skeletal muscle. Patients with HF have multiple clinical symptoms due to cardiac dysfunction. Recent studies demonstrated the mechanism and treatment strategy for HF, and multiple...

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Detalles Bibliográficos
Autores principales: Morotomi, Nobuo, Sakuma, Kunihiro, Sakai, Kotomi
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2021
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Acceso en línea:https://www.intechopen.com/chapters/76218
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Sumario:In patients with heart failure (HF), it is important to perform exercise therapy with a focus on the pathophysiology of skeletal muscle. Patients with HF have multiple clinical symptoms due to cardiac dysfunction. Recent studies demonstrated the mechanism and treatment strategy for HF, and multiple signaling pathways involved in HF result in reduced exercise capacity and skeletal muscle mass. On the other hand, exercise therapy for HF is known to inhibit the inflammatory cytokines and neurohumoral factors, and increase muscle mass. Therefore, in this chapter, we discuss the importance of exercise therapy for HF, with a focus on the pathophysiology of skeletal muscle.
ISBN:978-1-83968-650-4
DOI:10.5772/intechopen.97291