The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL

The aberrant tyrosine phosphorylation, either due to constitutive tyrosine kinases (TKs) or to inactivation of protein tyrosine phosphatases (PTPs), is a widespread feature of many cancerous cells. The BCR-ABL fusion protein, which arises from the Philadelphia chromosome, is a molecular distinct and...

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Detalles Bibliográficos

Autores principales:	Bracco, Enrico, Ali, M. Shahzad, Magnati, Stefano, Saglio, Giuseppe
Formato:	Capítulo de libro
Lenguaje:	inglés
Publicado:	IntechOpen 2021
Materias:	Health Sciences
Acceso en línea:	https://www.intechopen.com/chapters/76515
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!