Ovarian Cancer Genetics and the Implications
Ovarian cancers mostly arise sporadically, however about 20–25% of the cases arise as a part of hereditary syndromes. There are numerous mutations involved in the ovarian cancer development and more to be discovered. Knowing the pathogenic variants of the mutations present in the ovarian cancers are...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2021
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/76790 |
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| Sumario: | Ovarian cancers mostly arise sporadically, however about 20–25% of the cases arise as a part of hereditary syndromes. There are numerous mutations involved in the ovarian cancer development and more to be discovered. Knowing the pathogenic variants of the mutations present in the ovarian cancers are important in developing and practising of risk reduction strategies in asymptomatic carriers, genetic counselling, prognostication and decision on treatment. This chapter will focus on the various types of mutations found in ovarian cancers and their implications- when considering testing, treatment options and insight for the next level of Improvement in cancer care. |
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| ISBN: | 978-1-83968-743-3 |
| DOI: | 10.5772/intechopen.96488 |