Monoclonal Antibodies for Cancer Treatment

Therapeutic monoclonal antibodies have emerged in the 1990 decade as an important option for cancer treatment. These molecules have a diverse set of clinically relevant antitumor mechanisms, directly targeting tumor cells. It has been established as “standard of care” for several human cancers. This...

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Detalles Bibliográficos
Autores principales: Livinalli, Annemeri, Galvão, Taís Freire
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2021
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Acceso en línea:https://www.intechopen.com/chapters/76870
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Descripción
Sumario:Therapeutic monoclonal antibodies have emerged in the 1990 decade as an important option for cancer treatment. These molecules have a diverse set of clinically relevant antitumor mechanisms, directly targeting tumor cells. It has been established as “standard of care” for several human cancers. This chapter reviews the use of monoclonal antibodies in oncology and introduces available biosimilars. The requirements for biosimilar antibody development, mechanisms of action and current clinical applications for cancer treatment is also presented.
ISBN:978-1-83881-935-4
DOI:10.5772/intechopen.97915