Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1
This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journe...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2022
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| Acceso en línea: | https://www.intechopen.com/chapters/80021 |
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| _version_ | 1879164756379566080 |
|---|---|
| author | McKinley, Ryan Lucas |
| author_browse | McKinley, Ryan Lucas |
| author_facet | McKinley, Ryan Lucas |
| author_sort | McKinley, Ryan Lucas |
| building | IntechOpen |
| collection | Acceso abierto |
| description | This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journey through the ECS and CNS in various mammalian patient indicators to unmask this paradoxical effect. The specific biphasic/paradoxical manner in question was researched and inevitably identifies cannabis use that manipulates tryptophan uptake, serotonin release, and dopamine actuation. Therefore, a patient’s diet may demand a higher tryptophan and dopa-L supplementation to avoid a paradoxical agitation on the receptor level. This chapter explains the pathology of how cannabis consistently reacts in the ECS for every individual, only separated by metabolism and disruption/trauma in the ECS and CNS, implying that there was no found paradoxical effect existing in cannabis, but in the patient, and thus is perceived the same in every individual, only mediated by metabolism, environment (surroundings), and the exception for individuals who process stimulants and tryptophan and/or serotonin in a disrupted manner causing a perceived paradoxical effect or the build-up to and/or what will be referred to as ASR/ATD. The cannabis industry, growers/breeders, interpeners/cannabis sommeliers/bud tenders, and dispensaries need to continue to constantly strive for more knowledge, just as the researchers and FDA need to continue their work to understand the benefits of cannabis, and most importantly, all must work together to remove cannabis from the Schedule I and Schedule 2 classification. |
| doi_str_mv | 10.5772/intechopen.101555 |
| first_indexed | 2026-10-15T21:39:23Z |
| format | Book Chapter |
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<dc:title>Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1</dc:title>
<dc:creator>Ryan Lucas McKinley</dc:creator>
<dc:subject>Physical Sciences, Engineering and Technology</dc:subject>
<dc:description>This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journey through the ECS and CNS in various mammalian patient indicators to unmask this paradoxical effect. The specific biphasic/paradoxical manner in question was researched and inevitably identifies cannabis use that manipulates tryptophan uptake, serotonin release, and dopamine actuation. Therefore, a patient’s diet may demand a higher tryptophan and dopa-L supplementation to avoid a paradoxical agitation on the receptor level. This chapter explains the pathology of how cannabis consistently reacts in the ECS for every individual, only separated by metabolism and disruption/trauma in the ECS and CNS, implying that there was no found paradoxical effect existing in cannabis, but in the patient, and thus is perceived the same in every individual, only mediated by metabolism, environment (surroundings), and the exception for individuals who process stimulants and tryptophan and/or serotonin in a disrupted manner causing a perceived paradoxical effect or the build-up to and/or what will be referred to as ASR/ATD. The cannabis industry, growers/breeders, interpeners/cannabis sommeliers/bud tenders, and dispensaries need to continue to constantly strive for more knowledge, just as the researchers and FDA need to continue their work to understand the benefits of cannabis, and most importantly, all must work together to remove cannabis from the Schedule I and Schedule 2 classification.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2022-01-19</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/80021</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.101555</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-83969-346-5</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/10799 ; Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications</dc:source>
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| id | intech-80021 |
| institution | IntechOpen |
| isbn | 978-1-83969-346-5 |
| language | English |
| last_indexed | 2026-10-15T21:39:23Z |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
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| spelling | intech-800212022-01-19 Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 Ryan Lucas McKinley Physical Sciences, Engineering and Technology This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journey through the ECS and CNS in various mammalian patient indicators to unmask this paradoxical effect. The specific biphasic/paradoxical manner in question was researched and inevitably identifies cannabis use that manipulates tryptophan uptake, serotonin release, and dopamine actuation. Therefore, a patient’s diet may demand a higher tryptophan and dopa-L supplementation to avoid a paradoxical agitation on the receptor level. This chapter explains the pathology of how cannabis consistently reacts in the ECS for every individual, only separated by metabolism and disruption/trauma in the ECS and CNS, implying that there was no found paradoxical effect existing in cannabis, but in the patient, and thus is perceived the same in every individual, only mediated by metabolism, environment (surroundings), and the exception for individuals who process stimulants and tryptophan and/or serotonin in a disrupted manner causing a perceived paradoxical effect or the build-up to and/or what will be referred to as ASR/ATD. The cannabis industry, growers/breeders, interpeners/cannabis sommeliers/bud tenders, and dispensaries need to continue to constantly strive for more knowledge, just as the researchers and FDA need to continue their work to understand the benefits of cannabis, and most importantly, all must work together to remove cannabis from the Schedule I and Schedule 2 classification. IntechOpen 2022-01-19 Chapter, Part Of Book https://www.intechopen.com/chapters/80021 doi:10.5772/intechopen.101555 en ISBN:978-1-83969-346-5 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/10799 ; Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications |
| spellingShingle | Physical Sciences, Engineering and Technology McKinley, Ryan Lucas Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title | Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title_full | Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title_fullStr | Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title_full_unstemmed | Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title_short | Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 |
| title_sort | marijuana a journey through the endocannabinoid system unmasking the paradoxical effect part 1 |
| topic | Physical Sciences, Engineering and Technology |
| url | https://www.intechopen.com/chapters/80021 |
| work_keys_str_mv | AT mckinleyryanlucas marijuanaajourneythroughtheendocannabinoidsystemunmaskingtheparadoxicaleffectpart1 |