Tumor Angiogenesis in Pituitary Adenoma
The role of angiogenesis in pituitary tumor development used to be questioned, since pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinoma...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2022
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| Acceso en línea: | https://www.intechopen.com/chapters/80121 |
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| _version_ | 1879164757920972800 |
|---|---|
| author | Yoshida, Daizo Teramoto, Akira |
| author_browse | Teramoto, Akira Yoshida, Daizo |
| author_facet | Yoshida, Daizo Teramoto, Akira |
| author_sort | Yoshida, Daizo |
| building | IntechOpen |
| collection | Acceso abierto |
| description | The role of angiogenesis in pituitary tumor development used to be questioned, since pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to noninvasive and microprolactinomas. We should know VEGF was found firstly in pituitary anterior lobe, then tumor angiogenesis must occur. Meanwhile the vascular arrangement raised by VEGF is irregular, that sometimes lead to pituitary apoplexy. In this chapter, hypoxia inducible factors (HIF), transcription factors regulating expression of several genes related to oxygen homeostasis are in response to hypoxic stress. We focus on tumor angiogenesis regulated by the signaling cascade in tumor angiogenesis in pituitary tumor. |
| doi_str_mv | 10.5772/intechopen.102377 |
| first_indexed | 2026-10-15T21:39:25Z |
| format | Book Chapter |
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<dc:title>Tumor Angiogenesis in Pituitary Adenoma</dc:title>
<dc:creator>Daizo Yoshida</dc:creator>
<dc:creator>Akira Teramoto</dc:creator>
<dc:subject>Life Sciences</dc:subject>
<dc:description>The role of angiogenesis in pituitary tumor development used to be questioned, since pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to noninvasive and microprolactinomas. We should know VEGF was found firstly in pituitary anterior lobe, then tumor angiogenesis must occur. Meanwhile the vascular arrangement raised by VEGF is irregular, that sometimes lead to pituitary apoplexy. In this chapter, hypoxia inducible factors (HIF), transcription factors regulating expression of several genes related to oxygen homeostasis are in response to hypoxic stress. We focus on tumor angiogenesis regulated by the signaling cascade in tumor angiogenesis in pituitary tumor.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2022-01-20</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/80121</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.102377</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80355-834-9</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/10833 ; Tumor Angiogenesis and Modulators</dc:source>
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| id | intech-80121 |
| institution | IntechOpen |
| isbn | 978-1-80355-834-9 |
| language | English |
| last_indexed | 2026-10-15T21:39:25Z |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-801212022-01-20 Tumor Angiogenesis in Pituitary Adenoma Daizo Yoshida Akira Teramoto Life Sciences The role of angiogenesis in pituitary tumor development used to be questioned, since pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to noninvasive and microprolactinomas. We should know VEGF was found firstly in pituitary anterior lobe, then tumor angiogenesis must occur. Meanwhile the vascular arrangement raised by VEGF is irregular, that sometimes lead to pituitary apoplexy. In this chapter, hypoxia inducible factors (HIF), transcription factors regulating expression of several genes related to oxygen homeostasis are in response to hypoxic stress. We focus on tumor angiogenesis regulated by the signaling cascade in tumor angiogenesis in pituitary tumor. IntechOpen 2022-01-20 Chapter, Part Of Book https://www.intechopen.com/chapters/80121 doi:10.5772/intechopen.102377 en ISBN:978-1-80355-834-9 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/10833 ; Tumor Angiogenesis and Modulators |
| spellingShingle | Life Sciences Yoshida, Daizo Teramoto, Akira Tumor Angiogenesis in Pituitary Adenoma |
| title | Tumor Angiogenesis in Pituitary Adenoma |
| title_full | Tumor Angiogenesis in Pituitary Adenoma |
| title_fullStr | Tumor Angiogenesis in Pituitary Adenoma |
| title_full_unstemmed | Tumor Angiogenesis in Pituitary Adenoma |
| title_short | Tumor Angiogenesis in Pituitary Adenoma |
| title_sort | tumor angiogenesis in pituitary adenoma |
| topic | Life Sciences |
| url | https://www.intechopen.com/chapters/80121 |
| work_keys_str_mv | AT yoshidadaizo tumorangiogenesisinpituitaryadenoma AT teramotoakira tumorangiogenesisinpituitaryadenoma |