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Molecular Epidemiology of High-Risk Human Papillomavirus Infection in Burkina Faso

The aim of the present study was to determine the distribution of high-risk human papillomavirus (HR-HPV) genotypes in childbearing age women, teenage girls, HIV-infected women, women with high-grade precancerous lesions and cervical cancer, sex workers, men, and otolaryngology tumor cases in Burkin...

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Autores principales: Zohoncon, Théodora Mahoukèdè, Ouedraogo, Rogomenoma Alice, Djigma, Florencia Wendkuuni, Traore, Lassina, Ouedraogo, Teega-Wendé Clarisse, Ilboudo, Maimouna, Ilboudo, Regine, Salambanga, Catherine, Guigma, Sindimalgdé Patricia, Tovo, Sessi Frida, Traore, Mah Alima Esther, Bado, Prosper, Kande, Ali, Bisseye, Cyrille, Ouattara, Abdoul Karim, Traore, Ina Marie Angèle, Ouermi, Djeneba, Sagna, Tani, Yonli, Albert Théophane, Nadembega, Wendyam Marie Christelle, Obiri-Yeboah, Dorcas, Gyebre, Yvette Marie Chantal, Lompo, Olga Mélanie, Ouedraogo, Charlemagne Marie Ragnag-Newende, Simpore, Jacques
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2022
Materias:
Health Sciences
Acceso en línea:https://www.intechopen.com/chapters/80759
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Sumario:The aim of the present study was to determine the distribution of high-risk human papillomavirus (HR-HPV) genotypes in childbearing age women, teenage girls, HIV-infected women, women with high-grade precancerous lesions and cervical cancer, sex workers, men, and otolaryngology tumor cases in Burkina Faso. This descriptive cross-sectional study with several target groups, consisted of 2386 samples from Burkina Faso. HR-HPV genotypes were characterized using real-time multiplex PCR. The prevalence of HR-HPV ranged from 15.63 to 72.31% depending on the target population and the nature of the samples. The most predominant genotypes in descending order were HPV-56, HPV-52, HPV-39, HPV-59, HPV-51, HPV-35, HPV-31, HPV-18, HPV-68, HPV-16, HPV-66, HPV-58, HPV-45, and HPV-33. The results of the present study show a wide variation in the distribution of HR-HPV genotypes in Burkina Faso. Genotypes 16 and 18 covered by HPV vaccines only accounted for 32.23% of HR-HPV cases.
ISBN:978-1-83969-842-2
DOI:10.5772/intechopen.102327

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