Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination
Pneumococcal carriage is a prerequisite for invasive and non-invasive infections, where children and elderly are the most vulnerable groups. Aims: Determine rates of carriage, resistance, and coverage of the pneumococcal conjugate vaccines (PCVs) in children attending day care centers (DCC) in north...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2022
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| Acceso en línea: | https://www.intechopen.com/chapters/81821 |
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| _version_ | 1879164822521643008 |
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| author | Al-Lahham, Adnan |
| author_browse | Al-Lahham, Adnan |
| author_facet | Al-Lahham, Adnan |
| author_sort | Al-Lahham, Adnan |
| building | IntechOpen |
| collection | Acceso abierto |
| description | Pneumococcal carriage is a prerequisite for invasive and non-invasive infections, where children and elderly are the most vulnerable groups. Aims: Determine rates of carriage, resistance, and coverage of the pneumococcal conjugate vaccines (PCVs) in children attending day care centers (DCC) in north Jordan. Methods: Nasopharyngeal swabs (NP) were taken from healthy Jordanian children from north Jordan with ages ranging from 1 month to 14 years in the period from 2008 to 2019. Classical methods were used for cultivation, identification, resistance testing, and serotyping. Results: 1866 NP swabs were tested with carriage rate 39.3% (733 isolates). Resistance was variable; however, it showed highest rates for penicillin (89.3%) and trimethoprim-sulfamethoxazole (73.0%). Serotype 19F predominates with 17.6% of all serotypes. Coverage of the future PCV20 was 73.1% compared to the old PCV7 (41.7%). About 493 cases had a previous 1–3 PCV7 injections, among which 256 (51.9%) cases were pneumococcal carriers, distributed as non-PCV vaccine serotypes (31.6%), and with PCV types (68.4%). Conclusions: The potential inclusion of the PCV vaccination in the national immunization program of the country is necessary. |
| doi_str_mv | 10.5772/intechopen.104999 |
| first_indexed | 2026-10-15T21:40:27Z |
| format | Book Chapter |
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<dc:title>Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination</dc:title>
<dc:creator>Adnan Al-Lahham</dc:creator>
<dc:subject>Health Sciences</dc:subject>
<dc:description>Pneumococcal carriage is a prerequisite for invasive and non-invasive infections, where children and elderly are the most vulnerable groups. Aims: Determine rates of carriage, resistance, and coverage of the pneumococcal conjugate vaccines (PCVs) in children attending day care centers (DCC) in north Jordan. Methods: Nasopharyngeal swabs (NP) were taken from healthy Jordanian children from north Jordan with ages ranging from 1 month to 14 years in the period from 2008 to 2019. Classical methods were used for cultivation, identification, resistance testing, and serotyping. Results: 1866 NP swabs were tested with carriage rate 39.3% (733 isolates). Resistance was variable; however, it showed highest rates for penicillin (89.3%) and trimethoprim-sulfamethoxazole (73.0%). Serotype 19F predominates with 17.6% of all serotypes. Coverage of the future PCV20 was 73.1% compared to the old PCV7 (41.7%). About 493 cases had a previous 1–3 PCV7 injections, among which 256 (51.9%) cases were pneumococcal carriers, distributed as non-PCV vaccine serotypes (31.6%), and with PCV types (68.4%). Conclusions: The potential inclusion of the PCV vaccination in the national immunization program of the country is necessary.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2022-05-19</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/81821</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.104999</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-83768-943-9</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/12880 ; Infectious Diseases Annual Volume 2022</dc:source>
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| id | intech-81821 |
| institution | IntechOpen |
| isbn | 978-1-83768-943-9 |
| language | English |
| last_indexed | 2026-10-15T21:40:27Z |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-818212022-05-19 Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination Adnan Al-Lahham Health Sciences Pneumococcal carriage is a prerequisite for invasive and non-invasive infections, where children and elderly are the most vulnerable groups. Aims: Determine rates of carriage, resistance, and coverage of the pneumococcal conjugate vaccines (PCVs) in children attending day care centers (DCC) in north Jordan. Methods: Nasopharyngeal swabs (NP) were taken from healthy Jordanian children from north Jordan with ages ranging from 1 month to 14 years in the period from 2008 to 2019. Classical methods were used for cultivation, identification, resistance testing, and serotyping. Results: 1866 NP swabs were tested with carriage rate 39.3% (733 isolates). Resistance was variable; however, it showed highest rates for penicillin (89.3%) and trimethoprim-sulfamethoxazole (73.0%). Serotype 19F predominates with 17.6% of all serotypes. Coverage of the future PCV20 was 73.1% compared to the old PCV7 (41.7%). About 493 cases had a previous 1–3 PCV7 injections, among which 256 (51.9%) cases were pneumococcal carriers, distributed as non-PCV vaccine serotypes (31.6%), and with PCV types (68.4%). Conclusions: The potential inclusion of the PCV vaccination in the national immunization program of the country is necessary. IntechOpen 2022-05-19 Chapter, Part Of Book https://www.intechopen.com/chapters/81821 doi:10.5772/intechopen.104999 en ISBN:978-1-83768-943-9 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/12880 ; Infectious Diseases Annual Volume 2022 |
| spellingShingle | Health Sciences Al-Lahham, Adnan Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title | Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title_full | Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title_fullStr | Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title_full_unstemmed | Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title_short | Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination |
| title_sort | pneumococcal carriage in jordanian children and the importance of vaccination |
| topic | Health Sciences |
| url | https://www.intechopen.com/chapters/81821 |
| work_keys_str_mv | AT allahhamadnan pneumococcalcarriageinjordanianchildrenandtheimportanceofvaccination |