p53 Tumor Suppressor: Functional Regulation and Role in Gene Therapy

p53, a homo-tetrameric protein found in mammalian cells, derives its name from the fact that it settles at around 53KDa position in SDS-PAGE, due to a “kink” in its structure. In its functional state, p53 forms a homo-tetramer and binds to the promoters of a wide array of genes. Binding of p53 downr...

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Autores principales:	Farooq, Zeenat, Wani, Shahnawaz, Ragunathrao, Vijay Avin Balaji, Kochhar, Rakesh, Anwar, Mumtaz
Formato:	Capítulo de libro
Lenguaje:	inglés
Publicado:	IntechOpen 2022
Materias:	Life Sciences
Acceso en línea:	https://www.intechopen.com/chapters/82259
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