A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis

In this chapter, we describe the possible link between gut microbiota, melatonin, and breast cancer disease. It is widely described that changes in melatonin production due to circadian disruption is one of the causes of breast cancer. In addition, recently it is described that dysbiosis caused by c...

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Autores principales: González-González, Alicia, Laborda-Illanes, Aurora, Boutriq, Soukaina, Sánchez-Alcoholado, Lidia, Castellano-Castillo, Daniel, Plaza-Andrades, Isaac, Peralta-Linero, Jesús, Queipo-Ortuño, María Isabel
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Lenguaje:inglés
Publicado: IntechOpen 2022
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Acceso en línea:https://www.intechopen.com/chapters/82721
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author González-González, Alicia
Laborda-Illanes, Aurora
Boutriq, Soukaina
Sánchez-Alcoholado, Lidia
Castellano-Castillo, Daniel
Plaza-Andrades, Isaac
Peralta-Linero, Jesús
Queipo-Ortuño, María Isabel
author_browse Boutriq, Soukaina
Castellano-Castillo, Daniel
González-González, Alicia
Laborda-Illanes, Aurora
Peralta-Linero, Jesús
Plaza-Andrades, Isaac
Queipo-Ortuño, María Isabel
Sánchez-Alcoholado, Lidia
author_facet González-González, Alicia
Laborda-Illanes, Aurora
Boutriq, Soukaina
Sánchez-Alcoholado, Lidia
Castellano-Castillo, Daniel
Plaza-Andrades, Isaac
Peralta-Linero, Jesús
Queipo-Ortuño, María Isabel
author_sort González-González, Alicia
building IntechOpen
collection Acceso abierto
description In this chapter, we describe the possible link between gut microbiota, melatonin, and breast cancer disease. It is widely described that changes in melatonin production due to circadian disruption is one of the causes of breast cancer. In addition, recently it is described that dysbiosis caused by changes in the gut microbiota composition could be as well constitute an important factor to induce breast cancer. The dysbiosis process, in turn, induces the stimulation of kynurenine pathway, leading to reduced circulating melatonin levels. Therefore, in this chapter we deep into the relationship between circadian disruption, dysbiosis, and breast cancer disease. This constitutes an important step in the therapeutic approach and prevention of this pathology.
doi_str_mv 10.5772/intechopen.106068
first_indexed 2026-10-15T21:39:59Z
format Book Chapter
fullrecord <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-82721</identifier><datestamp>2022-07-25</datestamp> <dc:title>A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis</dc:title> <dc:creator>Alicia González-González</dc:creator> <dc:creator>Aurora Laborda-Illanes</dc:creator> <dc:creator>Soukaina Boutriq</dc:creator> <dc:creator>Lidia Sánchez-Alcoholado</dc:creator> <dc:creator>Daniel Castellano-Castillo</dc:creator> <dc:creator>Isaac Plaza-Andrades</dc:creator> <dc:creator>Jesús Peralta-Linero</dc:creator> <dc:creator>María Isabel Queipo-Ortuño</dc:creator> <dc:subject>Health Sciences</dc:subject> <dc:description>In this chapter, we describe the possible link between gut microbiota, melatonin, and breast cancer disease. It is widely described that changes in melatonin production due to circadian disruption is one of the causes of breast cancer. In addition, recently it is described that dysbiosis caused by changes in the gut microbiota composition could be as well constitute an important factor to induce breast cancer. The dysbiosis process, in turn, induces the stimulation of kynurenine pathway, leading to reduced circulating melatonin levels. Therefore, in this chapter we deep into the relationship between circadian disruption, dysbiosis, and breast cancer disease. This constitutes an important step in the therapeutic approach and prevention of this pathology.</dc:description> <dc:publisher>IntechOpen</dc:publisher> <dc:date>2022-07-25</dc:date> <dc:type>Chapter, Part Of Book</dc:type> <dc:identifier>https://www.intechopen.com/chapters/82721</dc:identifier> <dc:identifier>doi:10.5772/intechopen.106068</dc:identifier> <dc:language>en</dc:language> <dc:relation>ISBN:978-1-80356-734-1</dc:relation> <dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights> <dc:source>https://www.intechopen.com/books/11707 ; Melatonin - Recent Updates</dc:source> </oai_dc:dc>
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isbn 978-1-80356-734-1
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last_indexed 2026-10-15T21:39:59Z
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spelling intech-827212022-07-25 A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis Alicia González-González Aurora Laborda-Illanes Soukaina Boutriq Lidia Sánchez-Alcoholado Daniel Castellano-Castillo Isaac Plaza-Andrades Jesús Peralta-Linero María Isabel Queipo-Ortuño Health Sciences In this chapter, we describe the possible link between gut microbiota, melatonin, and breast cancer disease. It is widely described that changes in melatonin production due to circadian disruption is one of the causes of breast cancer. In addition, recently it is described that dysbiosis caused by changes in the gut microbiota composition could be as well constitute an important factor to induce breast cancer. The dysbiosis process, in turn, induces the stimulation of kynurenine pathway, leading to reduced circulating melatonin levels. Therefore, in this chapter we deep into the relationship between circadian disruption, dysbiosis, and breast cancer disease. This constitutes an important step in the therapeutic approach and prevention of this pathology. IntechOpen 2022-07-25 Chapter, Part Of Book https://www.intechopen.com/chapters/82721 doi:10.5772/intechopen.106068 en ISBN:978-1-80356-734-1 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/11707 ; Melatonin - Recent Updates
spellingShingle Health Sciences
González-González, Alicia
Laborda-Illanes, Aurora
Boutriq, Soukaina
Sánchez-Alcoholado, Lidia
Castellano-Castillo, Daniel
Plaza-Andrades, Isaac
Peralta-Linero, Jesús
Queipo-Ortuño, María Isabel
A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title_full A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title_fullStr A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title_full_unstemmed A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title_short A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
title_sort promising challenge in the link between melatonin and breast cancer exploring the microbiome gut brain axis
topic Health Sciences
url https://www.intechopen.com/chapters/82721
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