Melatonin Pretreatment Effect in a Parkinson Disease Experimental Model Induced by the Inhalation of Manganese in Mice

Parkinson disease (PD) is characterized by dopaminergic neuron loss of the substantia nigra compacta (SNc) and motor alterations. Here, we used the experimental model of inhalation of the mixture of manganese chloride (MnCl2) and manganese acetate Mn (OAc)3 for inducing PD. This model causes bilater...

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Bibliographic Details
Main Authors: Avila-Costa, Maria Rosa, Rodríguez-Alcántara, Mariana Stephania, Gutierréz-Valdez, Ana Luisa, Ordoñez-Librado, José Luis, Rodríguez-Lara, Vianey, Reynoso-Erazo, Leonardo, Dorado-Martínez, Claudia, Caballero, Cesar Alfonso Garcia, Montiel-Flores, Enrique, Sanchez-Betancourt, Javier, Tron-Alvarez, Rocío, Aley-Medina, Patricia, Espinosa-Villanueva, Jesús
Format: Book Chapter
Language:English
Published: IntechOpen 2022
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Online Access:https://www.intechopen.com/chapters/82761
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