The “Irony” of Ferroptosis: A Review on Neurological Challenges
Ferroptosis in recent days has gained high impact due to its implication in inducing several neurological challenges. Impairment of iron homeostasis (mainly surplus iron deposition) is the key reason for the induction of the ferroptotic cell death. This type of programmed cell death in the neurons c...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2022
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/84938 |
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| Sumario: | Ferroptosis in recent days has gained high impact due to its implication in inducing several neurological challenges. Impairment of iron homeostasis (mainly surplus iron deposition) is the key reason for the induction of the ferroptotic cell death. This type of programmed cell death in the neurons can trigger neuropathological abnormalities. Ferroptosis has been given clinical importance, where biomedical researchers are working on the pathological detection of ferroptosis and finding clinical ways to arrest it. In this review, we have elucidated the impact of ferroptotic cell death on the pathophysiology of several neurological challenges. |
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| ISBN: | 978-1-83768-244-7 |
| DOI: | 10.5772/intechopen.108737 |