RET Proto-Oncogene Mutations: Impact on Diagnosis, Treatment and Prognosis of MTC

Variants of MTC result from different mutations in exons of the RET gene. RET proto-oncogene is activated by a DNA rearrangement and it is one of the first tyrosine kinase receptor (RTK) proteins found to play a role in neoplasia. Early detection using genetic screening has become the gold standard...

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Autores principales: Heydarzadeh, Shabnam, Hedayati, Mehdi
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2023
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Acceso en línea:https://www.intechopen.com/chapters/85189
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