Drug Delivery of Corticosteroids
In this chapter, we will study how we were able to place drugs from the family of corticosteroids in the places where the drug is intended to be affected during the surgery. It was also possible to control the release of accumulated quantities of dexamethasone by coating it with some soluble polymer...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2022
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/85228 |
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| Sumario: | In this chapter, we will study how we were able to place drugs from the family of corticosteroids in the places where the drug is intended to be affected during the surgery. It was also possible to control the release of accumulated quantities of dexamethasone by coating it with some soluble polymers such as chitosan. We used samples of bioglass grafted with chitosan polymer to which different percentages of dexamethasone (Dexa) were added (5, 10, and 15%). In addition, the cumulative doses emitted from the samples were calculated by means of statistical functions and using the ultraviolet device. This was also tested on the plasma fluid of the human-simulating body fluid (SBF), and it was confirmed that the appropriate amounts of Dexa were emitted over a period of (1, 2, 4, 8, 16, 21, and 33) days. Due to its shown efficacy in simulating in liquid of the human body (SBF), we aim to put it within the human body as soon as feasible. |
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| ISBN: | 978-1-83768-625-4 |
| DOI: | 10.5772/intechopen.109085 |