Neuroimmunopathology in Toxoplasmic Encephalitis
Toxoplasma gondii is a zoonotic protozoan parasite that causes mortality because of significant neuropathology. It is widespread in neonatal infections. Although the neuroimmunopathogenesis of toxoplasmic encephalitis (TE) has been studied for many years, it is still not completely understood, showi...
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
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IntechOpen
2023
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| Acceso en línea: | https://www.intechopen.com/chapters/85605 |
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| _version_ | 1879164791265689600 |
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| author | Dincel, Gungor Cagdas Alouffi, Abdulaziz Olayan, Ebtesam M. Al Tellez-Isaias, Guillermo El-Ashram, Saeed |
| author_browse | Alouffi, Abdulaziz Dincel, Gungor Cagdas El-Ashram, Saeed Olayan, Ebtesam M. Al Tellez-Isaias, Guillermo |
| author_facet | Dincel, Gungor Cagdas Alouffi, Abdulaziz Olayan, Ebtesam M. Al Tellez-Isaias, Guillermo El-Ashram, Saeed |
| author_sort | Dincel, Gungor Cagdas |
| building | IntechOpen |
| collection | Acceso abierto |
| description | Toxoplasma gondii is a zoonotic protozoan parasite that causes mortality because of significant neuropathology. It is widespread in neonatal infections. Although the neuroimmunopathogenesis of toxoplasmic encephalitis (TE) has been studied for many years, it is still not completely understood, showing the disease’s severity. The urge to write this chapter comes at this stage. The sections covered in this chapter show the pathogenesis that has been established and characterized so far. The involvement of astrocytes and microglia in the development of neuropathology, which begins with tachyzoites crossing the blood-brain barrier during acute infection, has been explored. The molecular mechanism between schizophrenia and TE has been thoroughly proven. Uncovering the molecular pathogenesis of TE is critical for both understanding neuropathology and elucidating the link between neuropsychiatric diseases. Each part covered here is expected to contribute to developing novel therapeutic agents for the treatment and maybe prevention of neuropathology. The pathogenesis of the steady progression of encephalitis has been meticulously revealed. Thus, this chapter will offer significant insight into developing novel treatments for all organisms suffering from this disease. |
| doi_str_mv | 10.5772/intechopen.109341 |
| first_indexed | 2026-10-15T21:39:57Z |
| format | Book Chapter |
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<dc:title>Neuroimmunopathology in Toxoplasmic Encephalitis</dc:title>
<dc:creator>Gungor Cagdas Dincel</dc:creator>
<dc:creator>Abdulaziz Alouffi</dc:creator>
<dc:creator>Ebtesam M. Al Olayan</dc:creator>
<dc:creator>Guillermo Tellez-Isaias</dc:creator>
<dc:creator>Saeed El-Ashram</dc:creator>
<dc:subject>Life Sciences</dc:subject>
<dc:description>Toxoplasma gondii is a zoonotic protozoan parasite that causes mortality because of significant neuropathology. It is widespread in neonatal infections. Although the neuroimmunopathogenesis of toxoplasmic encephalitis (TE) has been studied for many years, it is still not completely understood, showing the disease’s severity. The urge to write this chapter comes at this stage. The sections covered in this chapter show the pathogenesis that has been established and characterized so far. The involvement of astrocytes and microglia in the development of neuropathology, which begins with tachyzoites crossing the blood-brain barrier during acute infection, has been explored. The molecular mechanism between schizophrenia and TE has been thoroughly proven. Uncovering the molecular pathogenesis of TE is critical for both understanding neuropathology and elucidating the link between neuropsychiatric diseases. Each part covered here is expected to contribute to developing novel therapeutic agents for the treatment and maybe prevention of neuropathology. The pathogenesis of the steady progression of encephalitis has been meticulously revealed. Thus, this chapter will offer significant insight into developing novel treatments for all organisms suffering from this disease.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2023-02-06</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/85605</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.109341</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80356-494-4</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/11635 ; Towards New Perspectives on Toxoplasma gondii</dc:source>
</oai_dc:dc> |
| id | intech-85605 |
| institution | IntechOpen |
| isbn | 978-1-80356-494-4 |
| language | English |
| last_indexed | 2026-10-15T21:39:57Z |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-856052023-02-06 Neuroimmunopathology in Toxoplasmic Encephalitis Gungor Cagdas Dincel Abdulaziz Alouffi Ebtesam M. Al Olayan Guillermo Tellez-Isaias Saeed El-Ashram Life Sciences Toxoplasma gondii is a zoonotic protozoan parasite that causes mortality because of significant neuropathology. It is widespread in neonatal infections. Although the neuroimmunopathogenesis of toxoplasmic encephalitis (TE) has been studied for many years, it is still not completely understood, showing the disease’s severity. The urge to write this chapter comes at this stage. The sections covered in this chapter show the pathogenesis that has been established and characterized so far. The involvement of astrocytes and microglia in the development of neuropathology, which begins with tachyzoites crossing the blood-brain barrier during acute infection, has been explored. The molecular mechanism between schizophrenia and TE has been thoroughly proven. Uncovering the molecular pathogenesis of TE is critical for both understanding neuropathology and elucidating the link between neuropsychiatric diseases. Each part covered here is expected to contribute to developing novel therapeutic agents for the treatment and maybe prevention of neuropathology. The pathogenesis of the steady progression of encephalitis has been meticulously revealed. Thus, this chapter will offer significant insight into developing novel treatments for all organisms suffering from this disease. IntechOpen 2023-02-06 Chapter, Part Of Book https://www.intechopen.com/chapters/85605 doi:10.5772/intechopen.109341 en ISBN:978-1-80356-494-4 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/11635 ; Towards New Perspectives on Toxoplasma gondii |
| spellingShingle | Life Sciences Dincel, Gungor Cagdas Alouffi, Abdulaziz Olayan, Ebtesam M. Al Tellez-Isaias, Guillermo El-Ashram, Saeed Neuroimmunopathology in Toxoplasmic Encephalitis |
| title | Neuroimmunopathology in Toxoplasmic Encephalitis |
| title_full | Neuroimmunopathology in Toxoplasmic Encephalitis |
| title_fullStr | Neuroimmunopathology in Toxoplasmic Encephalitis |
| title_full_unstemmed | Neuroimmunopathology in Toxoplasmic Encephalitis |
| title_short | Neuroimmunopathology in Toxoplasmic Encephalitis |
| title_sort | neuroimmunopathology in toxoplasmic encephalitis |
| topic | Life Sciences |
| url | https://www.intechopen.com/chapters/85605 |
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