Upgrading Non-Conventional Yeasts into Valuable Biofactories

The use of synthetic biology on yeasts has enhanced the production of commercially relevant chemicals, from biofuels to recombinant therapeutic proteins, to name just a few. Despite most of these advances had already been studied and described in Saccharomyces cerevisiae, during the last years the a...

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Autores principales: Castillo-Mendieta, Kevin, Arias, Jimmy, Gonzales-Zubiate, Fernando
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Publicado: IntechOpen 2023
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Acceso en línea:https://www.intechopen.com/chapters/86021
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author Castillo-Mendieta, Kevin
Arias, Jimmy
Gonzales-Zubiate, Fernando
author_browse Arias, Jimmy
Castillo-Mendieta, Kevin
Gonzales-Zubiate, Fernando
author_facet Castillo-Mendieta, Kevin
Arias, Jimmy
Gonzales-Zubiate, Fernando
author_sort Castillo-Mendieta, Kevin
building IntechOpen
collection Acceso abierto
description The use of synthetic biology on yeasts has enhanced the production of commercially relevant chemicals, from biofuels to recombinant therapeutic proteins, to name just a few. Despite most of these advances had already been studied and described in Saccharomyces cerevisiae, during the last years the attention has turned to the use of alternative expression systems with a higher yield and quality such as non-conventional yeasts. Recently, there has been an increase in studies about non-conventional yeasts due to advantages based on their natural capacity to tolerate harsh conditions or the wide range of carbon sources they need during the generation of specific products. This chapter, therefore, aims to describe the current status of the most used non-conventional yeasts in metabolite production as well as the engineering behind them in order to optimize or regulate protein expression: Pichia pastoris, Kluyveromyces marxianus, Kluyveromyces lactis and Yarrowia lipolytica.
doi_str_mv 10.5772/intechopen.109903
first_indexed 2026-10-15T21:40:29Z
format Book Chapter
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spelling intech-860212023-02-21 Upgrading Non-Conventional Yeasts into Valuable Biofactories Kevin Castillo-Mendieta Jimmy Arias Fernando Gonzales-Zubiate Physical Sciences, Engineering and Technology The use of synthetic biology on yeasts has enhanced the production of commercially relevant chemicals, from biofuels to recombinant therapeutic proteins, to name just a few. Despite most of these advances had already been studied and described in Saccharomyces cerevisiae, during the last years the attention has turned to the use of alternative expression systems with a higher yield and quality such as non-conventional yeasts. Recently, there has been an increase in studies about non-conventional yeasts due to advantages based on their natural capacity to tolerate harsh conditions or the wide range of carbon sources they need during the generation of specific products. This chapter, therefore, aims to describe the current status of the most used non-conventional yeasts in metabolite production as well as the engineering behind them in order to optimize or regulate protein expression: Pichia pastoris, Kluyveromyces marxianus, Kluyveromyces lactis and Yarrowia lipolytica. IntechOpen 2023-02-21 Chapter, Part Of Book https://www.intechopen.com/chapters/86021 doi:10.5772/intechopen.109903 en ISBN:978-0-85014-090-3 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/13264 ; Biotechnology - Biosensors, Biomaterials and Tissue Engineering Annual Volume 2023
spellingShingle Physical Sciences, Engineering and Technology
Castillo-Mendieta, Kevin
Arias, Jimmy
Gonzales-Zubiate, Fernando
Upgrading Non-Conventional Yeasts into Valuable Biofactories
title Upgrading Non-Conventional Yeasts into Valuable Biofactories
title_full Upgrading Non-Conventional Yeasts into Valuable Biofactories
title_fullStr Upgrading Non-Conventional Yeasts into Valuable Biofactories
title_full_unstemmed Upgrading Non-Conventional Yeasts into Valuable Biofactories
title_short Upgrading Non-Conventional Yeasts into Valuable Biofactories
title_sort upgrading non conventional yeasts into valuable biofactories
topic Physical Sciences, Engineering and Technology
url https://www.intechopen.com/chapters/86021
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AT ariasjimmy upgradingnonconventionalyeastsintovaluablebiofactories
AT gonzaleszubiatefernando upgradingnonconventionalyeastsintovaluablebiofactories