Long-Term Beta-Blocker Therapy Outcomes in Acute and Chronic Stimulant Abuse
Fear of BBT (beta-blocker therapy) has initiated after a small amount of evidence proposing beta-blockers given during acute stimulant toxicity may create an unopposed alpha-receptor stimulation leading to worse medical outcomes. The objective is to investigate how long-term BBT (both selective and...
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| Autor principal: | |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/86076 |
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| Sumario: | Fear of BBT (beta-blocker therapy) has initiated after a small amount of evidence proposing beta-blockers given during acute stimulant toxicity may create an unopposed alpha-receptor stimulation leading to worse medical outcomes. The objective is to investigate how long-term BBT (both selective and non-selective) affect cardiovascular outcomes compared to no BBT regarding prevention of stimulant-induced-cardiomyopathy. Method is review of most current medical literature. The use of either selective or non-selective beta-blockers to treat the acute effects of cocaine or methamphetamine toxicity demonstrates safety and efficacy. Long-term BBT either selective or non-selective shows success in the prevention of cardiomyopathy in cocaine users by demonstrating a lower rate of death, MI, hospital readmission and improvement of LVEF and NYHA functional class compared to no BBT use. Both selective and non-selective long-term BBT prevent the progression of cardiomyopathy in active cocaine users but not methamphetamine. |
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| ISBN: | 978-1-83969-857-6 |
| DOI: | 10.5772/intechopen.110082 |