Chemokines in Periodontal Diseases
Periodontal disease is a chronic multifactorial inflammatory disease affecting the tooth-supporting apparatus including the gingiva, alveolar bone, and periodontal ligament caused by specific microorganisms. Periodontal diseases are among the most widespread diseases in humans and are a major public...
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| Autores principales: | , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/86154 |
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| Sumario: | Periodontal disease is a chronic multifactorial inflammatory disease affecting the tooth-supporting apparatus including the gingiva, alveolar bone, and periodontal ligament caused by specific microorganisms. Periodontal diseases are among the most widespread diseases in humans and are a major public health problem due to complications caused by early tooth loss. The immunoinflammatory responses initiated by periodontopathogens to protect the host against periodontal infection cause the release of various proinflammatory and chemotactic cytokines, i.e., chemokines. Chemokines have been implicated in the immunopathogenesis of periodontal disease and are found in gingival tissue, GCF, plasma, and saliva in periodontal disease. This section aims to summarize the data concerning the role of chemokines in periodontal tissue inflammation. |
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| ISBN: | 978-1-80356-173-8 |
| DOI: | 10.5772/intechopen.106846 |