Current Trends in the GFD Follow-Up

A poor adherence to a gluten-free diet (GFD) have a negative impact on people with celiac disease (CD). However, committing to a gluten-free lifelong carries social and economic burden and, a high degree of knowledge, motivation and a continuous effort. It is essential that the patient understands i...

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Detalles Bibliográficos
Autores principales: Azkoaga, Irati Mendia, Cebolla, Ángel
Formato: Capítulo de libro
Lenguaje:inglés
Publicado: IntechOpen 2023
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Acceso en línea:https://www.intechopen.com/chapters/86300
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Sumario:A poor adherence to a gluten-free diet (GFD) have a negative impact on people with celiac disease (CD). However, committing to a gluten-free lifelong carries social and economic burden and, a high degree of knowledge, motivation and a continuous effort. It is essential that the patient understands its disease, how to perform a GFD and the consequences that entail if the patient is not followed in the long term. However, a large percentage of patients does not still achieve a complete mucosal healing, likely due to a poor adherence to the GFD. We describe the current tools for the control of adherence to a GFD, with a special focus on the detection of gluten immunogenic peptides (GIP) in feces and urine, as GIP detection allows direct evidence that the gluten that has been ingested. GIP are becoming useful biomarkers for this aim. Here, we summarize the current information about the main applications and limitations of the use of the GIP determinations in the follow up of celiac disease.
ISBN:978-1-83768-870-8
DOI:10.5772/intechopen.109954