Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies
The ovarian milieu, which includes increased vasculature, different growth factors, necessary hormone synthesis, and appropriate granulosa cell function, is essential for oocyte maturation. Keeping the microenvironment in a state of equilibrium is crucial for healthy ovarian function. However, as pe...
Guardado en:
| Autores principales: | , |
|---|---|
| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
|
| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/86471 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1879164798275420160 |
|---|---|
| author | Díez-Juan, Antonio Vladimirov, Iavor K. |
| author_browse | Díez-Juan, Antonio Vladimirov, Iavor K. |
| author_facet | Díez-Juan, Antonio Vladimirov, Iavor K. |
| author_sort | Díez-Juan, Antonio |
| building | IntechOpen |
| collection | Acceso abierto |
| description | The ovarian milieu, which includes increased vasculature, different growth factors, necessary hormone synthesis, and appropriate granulosa cell function, is essential for oocyte maturation. Keeping the microenvironment in a state of equilibrium is crucial for healthy ovarian function. However, as people age, their tissues rebuild less effectively, leading to an imbalance in the microenvironment’s homeostasis and ovarian fibrosis, which finally causes ovarian function to deteriorate. As a result, full restoration of ovarian microenvironment health is required to enhance ovarian function. The precise identification of the molecular pathways involved in ovarian aging can help to devise therapy techniques that can decrease ovarian decay and boost the amount and quality of oocytes available for IVF. Antioxidants, melatonin, growth hormones, and mitochondrial and cell therapy are among the available treatments. All of these treatments must be considered in light of every couple’s history and current biological parameters, and a personalized (patient-tailored) therapy program must be developed. In this chapter, we aim to give an overview on the identified mechanism involved in female reproductive aging and potential therapeutic approaches to amend reproductive efficiency. |
| doi_str_mv | 10.5772/intechopen.110524 |
| first_indexed | 2026-10-15T21:40:03Z |
| format | Book Chapter |
| fullrecord | <oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><identifier>intech-86471</identifier><datestamp>2023-03-10</datestamp>
<dc:title>Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies</dc:title>
<dc:creator>Antonio Díez-Juan</dc:creator>
<dc:creator>Iavor K. Vladimirov</dc:creator>
<dc:subject>Health Sciences</dc:subject>
<dc:description>The ovarian milieu, which includes increased vasculature, different growth factors, necessary hormone synthesis, and appropriate granulosa cell function, is essential for oocyte maturation. Keeping the microenvironment in a state of equilibrium is crucial for healthy ovarian function. However, as people age, their tissues rebuild less effectively, leading to an imbalance in the microenvironment’s homeostasis and ovarian fibrosis, which finally causes ovarian function to deteriorate. As a result, full restoration of ovarian microenvironment health is required to enhance ovarian function. The precise identification of the molecular pathways involved in ovarian aging can help to devise therapy techniques that can decrease ovarian decay and boost the amount and quality of oocytes available for IVF. Antioxidants, melatonin, growth hormones, and mitochondrial and cell therapy are among the available treatments. All of these treatments must be considered in light of every couple’s history and current biological parameters, and a personalized (patient-tailored) therapy program must be developed. In this chapter, we aim to give an overview on the identified mechanism involved in female reproductive aging and potential therapeutic approaches to amend reproductive efficiency.</dc:description>
<dc:publisher>IntechOpen</dc:publisher>
<dc:date>2023-03-10</dc:date>
<dc:type>Chapter, Part Of Book</dc:type>
<dc:identifier>https://www.intechopen.com/chapters/86471</dc:identifier>
<dc:identifier>doi:10.5772/intechopen.110524</dc:identifier>
<dc:language>en</dc:language>
<dc:relation>ISBN:978-1-80356-719-8</dc:relation>
<dc:rights>https://creativecommons.org/licenses/by/3.0/</dc:rights>
<dc:source>https://www.intechopen.com/books/11839 ; IVF Technologies and Infertility - Current Practices and New Perspectives</dc:source>
</oai_dc:dc> |
| id | intech-86471 |
| institution | IntechOpen |
| isbn | 978-1-80356-719-8 |
| language | English |
| last_indexed | 2026-10-15T21:40:03Z |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | oai_dc |
| spelling | intech-864712023-03-10 Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies Antonio Díez-Juan Iavor K. Vladimirov Health Sciences The ovarian milieu, which includes increased vasculature, different growth factors, necessary hormone synthesis, and appropriate granulosa cell function, is essential for oocyte maturation. Keeping the microenvironment in a state of equilibrium is crucial for healthy ovarian function. However, as people age, their tissues rebuild less effectively, leading to an imbalance in the microenvironment’s homeostasis and ovarian fibrosis, which finally causes ovarian function to deteriorate. As a result, full restoration of ovarian microenvironment health is required to enhance ovarian function. The precise identification of the molecular pathways involved in ovarian aging can help to devise therapy techniques that can decrease ovarian decay and boost the amount and quality of oocytes available for IVF. Antioxidants, melatonin, growth hormones, and mitochondrial and cell therapy are among the available treatments. All of these treatments must be considered in light of every couple’s history and current biological parameters, and a personalized (patient-tailored) therapy program must be developed. In this chapter, we aim to give an overview on the identified mechanism involved in female reproductive aging and potential therapeutic approaches to amend reproductive efficiency. IntechOpen 2023-03-10 Chapter, Part Of Book https://www.intechopen.com/chapters/86471 doi:10.5772/intechopen.110524 en ISBN:978-1-80356-719-8 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/11839 ; IVF Technologies and Infertility - Current Practices and New Perspectives |
| spellingShingle | Health Sciences Díez-Juan, Antonio Vladimirov, Iavor K. Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title | Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title_full | Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title_fullStr | Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title_full_unstemmed | Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title_short | Perspective Chapter: Ovarian Reproductive Aging and Rejuvenation Strategies |
| title_sort | perspective chapter ovarian reproductive aging and rejuvenation strategies |
| topic | Health Sciences |
| url | https://www.intechopen.com/chapters/86471 |
| work_keys_str_mv | AT diezjuanantonio perspectivechapterovarianreproductiveagingandrejuvenationstrategies AT vladimiroviavork perspectivechapterovarianreproductiveagingandrejuvenationstrategies |