Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors

The exploitation of alginate and its composites as immobilisation support matrices in multiple applications remains a promising field that has the potential to create advanced functional materials from sustainable natural sources. They are non-toxic, allow sol-gel transformation, are biocompatible,...

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Autores principales: Paul, Abraham Abbey, Markus, Victor, Kristollari, Kathelina, Marks, Robert S.
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Lenguaje:inglés
Publicado: IntechOpen 2023
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Acceso en línea:https://www.intechopen.com/chapters/86721
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author Paul, Abraham Abbey
Markus, Victor
Kristollari, Kathelina
Marks, Robert S.
author_browse Kristollari, Kathelina
Marks, Robert S.
Markus, Victor
Paul, Abraham Abbey
author_facet Paul, Abraham Abbey
Markus, Victor
Kristollari, Kathelina
Marks, Robert S.
author_sort Paul, Abraham Abbey
building IntechOpen
collection Acceso abierto
description The exploitation of alginate and its composites as immobilisation support matrices in multiple applications remains a promising field that has the potential to create advanced functional materials from sustainable natural sources. They are non-toxic, allow sol-gel transformation, are biocompatible, have remarkable ion exchange properties, are biodegradable, and are amenable to chemical functionalisation. Alginate and its derived composites have numerous biotechnological and biomedical applications, including biomolecule or cell immobilisation, tissue engineering, drug delivery, wound dressing, and biosensors. Alginate can rapidly crosslink into a stable 3D water-insoluble network called hydrogel with polyvalent cations. Blending alginate with other materials to produce composite materials with improved or novel physicochemical properties remains an ongoing research endeavour. For instance, natural and synthetic polymers or nanoparticles have been incorporated into alginate-yielding composite material with enhanced physical strength, controlled porosity, improved interaction between the alginate support and the biomolecules, and the impartation of other features such as electrical and magnetic responsiveness, among others. Immobilisation strategies are discussed herein, including their innovations and future research perspectives.
doi_str_mv 10.5772/intechopen.110737
first_indexed 2026-10-15T21:40:15Z
format Book Chapter
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spelling intech-867212023-04-10 Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors Abraham Abbey Paul Victor Markus Kathelina Kristollari Robert S. Marks Physical Sciences, Engineering and Technology The exploitation of alginate and its composites as immobilisation support matrices in multiple applications remains a promising field that has the potential to create advanced functional materials from sustainable natural sources. They are non-toxic, allow sol-gel transformation, are biocompatible, have remarkable ion exchange properties, are biodegradable, and are amenable to chemical functionalisation. Alginate and its derived composites have numerous biotechnological and biomedical applications, including biomolecule or cell immobilisation, tissue engineering, drug delivery, wound dressing, and biosensors. Alginate can rapidly crosslink into a stable 3D water-insoluble network called hydrogel with polyvalent cations. Blending alginate with other materials to produce composite materials with improved or novel physicochemical properties remains an ongoing research endeavour. For instance, natural and synthetic polymers or nanoparticles have been incorporated into alginate-yielding composite material with enhanced physical strength, controlled porosity, improved interaction between the alginate support and the biomolecules, and the impartation of other features such as electrical and magnetic responsiveness, among others. Immobilisation strategies are discussed herein, including their innovations and future research perspectives. IntechOpen 2023-04-10 Chapter, Part Of Book https://www.intechopen.com/chapters/86721 doi:10.5772/intechopen.110737 en ISBN:978-1-83768-691-9 https://creativecommons.org/licenses/by/3.0/ https://www.intechopen.com/books/12220 ; Alginate - Applications and Future Perspectives
spellingShingle Physical Sciences, Engineering and Technology
Paul, Abraham Abbey
Markus, Victor
Kristollari, Kathelina
Marks, Robert S.
Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title_full Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title_fullStr Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title_full_unstemmed Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title_short Alginate-Based Applications in Biotechnology with a Special Mention to Biosensors
title_sort alginate based applications in biotechnology with a special mention to biosensors
topic Physical Sciences, Engineering and Technology
url https://www.intechopen.com/chapters/86721
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AT markusvictor alginatebasedapplicationsinbiotechnologywithaspecialmentiontobiosensors
AT kristollarikathelina alginatebasedapplicationsinbiotechnologywithaspecialmentiontobiosensors
AT marksroberts alginatebasedapplicationsinbiotechnologywithaspecialmentiontobiosensors