The Role of the Gluten-Free Diet in the Development of Malignancies in Celiac Disease
Celiac disease (CD) is an autoimmune disorder that can lead to serious health consequences, including cancer. The gluten-free diet (GFD) is the primary treatment for CD and has been shown to lead to clinical remission of the disease. However, the effect of the GFD on cancer development in CD patient...
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| Autores principales: | , , |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/86839 |
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| Sumario: | Celiac disease (CD) is an autoimmune disorder that can lead to serious health consequences, including cancer. The gluten-free diet (GFD) is the primary treatment for CD and has been shown to lead to clinical remission of the disease. However, the effect of the GFD on cancer development in CD patients is not well understood. This narrative review analyzed observational studies investigating the association between cancer development and adherence to the GFD in CD patients. The most common cancer identified was non-Hodgkin’s lymphoma, followed by others such as colon carcinoma and thyroid cancer. Late diagnosis, type of cancer, and type of CD were factors relevant to the protective role of the GFD. However, there is still no consensus in the scientific literature regarding the GFD’s role in cancer development in CD. While some studies suggest a protective role, others have not identified an association between the GFD and cancer. More research is needed to understand the relationship between the GFD and cancer development in CD patients. Nonetheless, the GFD is essential for the clinical, serological, and histological remission of CD and improved quality of life. |
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| ISBN: | 978-1-83768-870-8 |
| DOI: | 10.5772/intechopen.110858 |