Biobetters: IFN-α2b Variants with Reduced Immunogenicity for the Treatment of Human Viral Diseases

For more than three decades, IFN-α2b has been widely used for the treatment of multiple human viral infections such as chronic hepatitis B and C, and certain types of cancers. However, IFN-α2b can be immunogenic, and these undesired immune responses can lead to a decrease in therapeutic efficacy. In...

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Bibliographic Details
Main Authors: Mufarrege, Eduardo F., Peña, Lucía C., Etcheverrigaray, Marina
Format: Book Chapter
Language:English
Published: IntechOpen 2023
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Online Access:https://www.intechopen.com/chapters/87341
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