Sepsis and Brain-Derived Neurotrophic Factor (BDNF): Exploring the Complex Connection
In recent studies, brain-derived neurotrophic factor (BDNF) become a very important position. Because it is now known that it is not just a hormone that is released from the hippocampus and which supports the differentiation and growth of newly formed nerve cells and synapses while maintaining the v...
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| Autor principal: | |
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| Formato: | Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
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| Materias: | |
| Acceso en línea: | https://www.intechopen.com/chapters/87399 |
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| Sumario: | In recent studies, brain-derived neurotrophic factor (BDNF) become a very important position. Because it is now known that it is not just a hormone that is released from the hippocampus and which supports the differentiation and growth of newly formed nerve cells and synapses while maintaining the vitality of existing neurons. Today BDNF was used as an indicator of severe sepsis and also in the follow-up of the disease. Moreover, BDNF is a potential anti-inflammatory agent which can be given like a medicament. In some studies, antiinflammatory effect was proven “in acute lung injury, in myocardial injury, in hepatorenal injury” triggered by sepsis. In this chapter, we will try to explain the BDNF effect in sepsis according to recent literature and update our knowledge. |
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| ISBN: | 978-1-83769-312-2 |
| DOI: | 10.5772/intechopen.112083 |